Newsletters

Alliance E-News is the official newsletter of the Alliance for Clinical Trials in Oncology. The quarterly newsletter focuses on current information about the Alliance, its policies and procedures, group meetings and activities, and other topics of interest to Alliance members.
 

• 2022

• Winter Vol 12 No 8 (December)
  • Message From Alliance Leadership
    Interim Group Chair - Suzanne George, MD
    Group Statistician - Sumithra Mandrekar, PhD
  • Group Chair Search -  Alliance for Clinical Trials in Oncology
  • Year In Review
    Spotlight on Recently Activated Alliance Trials
    Spotlight on Ongoing Alliance Trials
    Spotlight on Scientific Annual Meetings: 2022 SABCS & ASH
    Spotlight on Best Publications
    Spotlight on Alliance Trial Results
  • Alliance/Alliance Entities Holiday Closures
  • PDF
• Fall Vol 12 No 7 (October)
  • 2022 Alliance Fall Hybrid Group Meeting Convenes November 2-5
  • Update on Alliance Participant Engagement Portal (PEP)
  • November is National Lung Cancer Awareness Month
    A021901 (Bronchial Neuroendocrine Tumors)
    A081801 (ALCHEMIST chemo-IO)
    A082002 (Advanced Non-small Cell Lung Cancer)
    A151216 (ALCHEMIST)
    A171901 (Non-small Cell Lung Cancer in Older Adults)
  • Spotlight on Alliance Trials
    *Ongoing Trials
    A011801 (COMPASS HER2 RD/Breast Cancer)
    A021602 (CABINET/Advanced Neuroendocrine Tumors)
    A021804 (Advanced Pheochromocytoma and Paraganglioma)
    A031902 (CASPAR/Metastatic Castration-resistant Prostate Cancer)
  • Closed to Accrual (Alliance A031102 | TIGER)
  • October ASCO Plenary Series (AFT-05 | PALLAS)
  • PDF

• Fall Vol 12 No 6 (September)
  • Alliance Leadership Transition: Suzanne George, MD, Appointed Interim Group Chair
  • Alliance Welcomes Three New Patient Advocates
  • October is National Breast Cancer Awareness Month
    A011801 (COMPASS HER2 RD/Breast Cancer)
    A071701 (Genomically-guided Treatment in Brain Metastases)
    A191901 (Optimizing Endocrine Therapy)
    A221803 (Reducing Radiation Dermatitis)
    A231910CD (Patient-centered Communication in Breast Cancer)
  • Spotlight on Alliance Trials
    *Recently Activated Trials
    A212102 (Multicancer Early Detection Blood Tests)
    A032101 (Metastatic Hormone-sensitive Prostate Cancer)
    *Ongoing Trials
    A032002 (Metastatic Urothelial Cancer)
    A051902 (Peripheral T-cell Lymphoma)
    A081801 (Resected Non-small Cell Lung Cancer)
    A222001 (Hot Flashes in Men/Androgen Deprivation Therapy)
  • Announcements
    Registration Now Open: 2022 Alliance Fall Hybrid Group Meeting
    Call for Applications: Alliance CRP Committee Cadre Members
    Call for Proposals: Alliance Cancer Control Program Pilot Awards
  • October ASCO Plenary Series to Feature PALLAS (AFT-05) Study Update

  • Alliance in the News
    Alliance for Clinical Trials in Oncology Applauds Appointment of Monica M. Bertagnolli as NCI's New Director
    Interview with Patient on Alliance RadiCaL Study (A031801)
    Physical Activity in Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance)
    Novel Drug Delivery Systems for Patients With Advanced Prostate Cancer: A Focus on Radioligand Therapy and ADCs
    Immunoscore Is Prognostic in Low-Risk and High-Risk Stage III Colon Carcinomas Treated with Adjuvant Infusional Fluorouracil, Leucovorin, and Oxaliplatin in a Phase III Trial
    Acquired Genomic Alterations on First-Line Chemotherapy With Cetuximab in Advanced Colorectal Cancer: Circulating Tumor DNA Analysis of the CALGB/SWOG-80405 Trial (Alliance)
    Preoperative Combination Chemotherapy Improved Survival in Patients with Pancreatic Cancer
    Alliance Foundation Trials Study Finds Combination Hormonal Therapy Delivered in Finite Period Improves PSA Levels in Patients with Prostate Cancer 
    Alliance MCED Biobank Study May Provide Greater Understanding of How to Detect Multiple Cancers

  • PDF

• Summer Vol 12 No 5 (July)
  • Nursing in the Modern Clinical Trials Era
    Lisa A. Kottschade, MSN, APRN, CNP - Chair, Alliance Oncology Nursing Committee
  • July is National Sacroma and Bone Cancer Awareness Month
    A091902: Angiosarcoma
  • Spotlight on Alliance Trials
    *Recently Activated Trials
    A221803 (Reducing Radiation Dermatitis) - Breast Cancer
    A091903 (Resected Mucosal Melanoma)
    *Ongoing Trials
    A011801 (COMPASS HER2 RD/Breast Cancer)
    A021602 (CABINET/Advanced Neuroendocrine Tumors)
    A021804 (Advanced Pheochromocytoma and Paraganglioma)
    A031902 (CASPAR/Metastatic Castration-resistant Prostate Cancer)
    A071702 (Somatically Hypermutated Recurrent Glioblastoma)
    A081801 (Non-small Cell Lung Cancer)
  • Announcements
    Call for Nominations: Charles G. Moertel Lecture 2023
    2022 Alliance for Clinical Trials in Oncology Foundation Special Projects Allocation Awards
    Alliance Myeloma Committee Chair Appointment
    Alliance Board of Directors Approve New Program for Procedure-Based Therapy (PPBT)
    New Alliance Participant Engagement Portal to Launch Soon
  • Alliance in the News
    Inequities in Alliance Acute Leukemia Clinical Trial and Biobank Participation: Defining Targets for Intervention

    Predictive Biomarkers of Overall Survival in Patients with Metastatic Renal Cell Carcinoma Treated with IFNα ± Bevacizumab: Results from CALGB 90206 (Alliance)

    Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy with Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)

    Biomarker Development: Bedside to Bench

  • Alliance NCTN/NCORP/AFT at 2022 ASCO
  • PDF
• Spring Vol 12 No 4 (May)
  • Remembering Jeff A. Sloan, PhD
  • Alliance Spring Hybrid Group Meeting Convenes May 11-14
    Celebrating Our 10-Year Anniversary
  • Clinical Trials Day - May 20, 2022
  • Creating Surgical Standards to Improve Quality of Surgical Care
    Christina L. Roland, MD, MS - Chair, Alliance Cancer Care Standards Development Committee
    Kelly K. Hunt, MD - Director, Alliance/American College of Surgeons Clinical Research Program
  • Alliance Data and Safety Monitoring Board: Who Are We and What Do We Do?
    Jeffrey J. Kirshner, MD, FACP, FASCO
    Director of Research, HOACNY and Chair, Alliance Data and Safety Monitoring Board
  • Spotlight on Alliance Trials
    A071702 Somatically Hypermutated Recurrent Glioblastoma
    A171901 Non-small Cell Lung Cancer in Older Patients
  • May is . . . National Bladder Cancer Awareness Month
    A031701 Muscle-invasive Bladder Cancer
    A031803 CG-unresponsive Non-muscle Invasive Bladder Cancer
    A031901 Metastatic Urothelial Carcinoma
    A032001 MAIN-CAV: Metastatic Urothelial Carcinoma
    A032002 ART: Platinum iIeligible/Refractory Metastatic Urothelial Cancer

  • Alliance in the News
    ** A Wave of New Cancer Treatments Challenges Community Oncologists to Keep Up
    ** Geriatric Assessment for Older Adults Receiving Less Intensive Therapy for Acute Myeloid Leukemia: Report of CALGB 361101
    ** KDR Genetic Predictor of Toxicities Induced by Sorafenib and Regorafenib
    ** Sanofi Provides Update on Phase 2 Study Evaluating Amcenestrant in ER+/HER2- Advanced or Metastatic Breast Cancer

  • PDF Version

• Spring Vol 12 No 3 (March)
  • Newly Implemented Changes Improve Alliance Audit Process
    Scott H. Okuno, MD - Chair, Alliance Audit Committee
    Kurombi Wade-Oliver, CCRP - Director, Alliance Quality Management and Audit Program
  • Spotlight on Alliance Trials
    A022001 (Pancreatic Endocrine Tumors)
    A032001/MAIN CAV Study (Metastatic Urothelial Cancer)
  • April is . . . National Cancer Control Month
    Cancer in the Older Adult | Cancer Care Delivery Research
    Health Disparities | Health Outcomes
    Prevention | Spymtom Intervention
  • Alliance Foundation Funding Opportunity
  • FY22 BIQSFP Funding Opportunity

  • Alliance in the News
    ** Molecular, Clinical, and Prognostic Implications of PTPN11 Mutations in Acute Myeloid Leukemia
    ** Living with and Learning about Neuroendocrine Tumors: A Conversation with Dr. Jaydira Del Rivero
    ** Emerging Adjuvant Therapies in Renal Cell Carcinoma Post-ASCO GU ’22
    ** A Wave of New Cancer Treatments Challenges Community Oncologists to Keep Up

  • PDF Version

• Winter Vol 12 No 2 (February)
  • Message From the Group Statistician - Sumithra J. Mandrekar, PhD
  • Navigating Ethical Dilemmas, Guiding Investigators During the Conduct of Oncology Clinical Trials
    Fay J. Hlubocky, PhD, MA, and Jeffrey M. Peppercorn, MD, MPH - Co-Chairs, Alliance Ethics Committee
  • Increased Skill Level, Training of Clinical Research Professionals Now Required to Meet Complexities of New Clinical Trials
    Jennifer Dill, CCRP - Chair, Alliance Clinical Research Professionals Committee
     
  • Spotlight on Alliance Trials
    A211801 (BRCA-P Breast Cancer Prevention Study)
    
    March is . . .
  • National Colorectal Cancer Awareness Month
    A021502: ATOMIC (DNA Mismatch Repair)
    A021703: SOLARIS (Vitamin D Supplementation)
    A221805 (Peripheral Neuropathy)
  • National Kidney Cancer Awareness Month
    A301704: PDIGREE (Metastatic Untreated RCC)
    A031801: RadiCaL (Advanced RCC/Bone Metastasis)
     
  • Alliance Foundation Funding Opportunity
     

  • Alliance in the News
    Alliance A011502 | Aspirin Doesn’t Improve iDFS in Breast Cancer
    Alliance A021804 | NCI Clinical Trial Spotlight: Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer
    AFT-05 (PALLAS) | Safety of Adjuvant CDK4/6 Inhibitors During the COVID-19 Pandemic
    CALGB 90601 | Results of Bevacizumab-Chemotherapy Combinations for Patients with Advanced Urothelial Cancer - Expert Commentary
    Alliance A041202 | Anti-CD20 Monoclonal Antibodies for Chronic Lymphocytic Leukemia
    New Cancer Research | NCI Seeks to Develop Clinical Trial of MCED Tests
    Cancer Research Opinion | Congressional Inaction Harms Federally Funded Oncology Research and Our Patients: The Time for the Cancer Community to Act is Now
    Alliance Group Chair | Monica Bertagnolli, M.D., FACS joins Prevent Cancer Board of Directors
    Alliance Ethics Committee Co-Chair | Jeffrey Peppercorn, MD, MPH, Named Editor-in-Chief of JCO Oncology Practice
    Alliance Committee Co-Chair | Ian E. Krop, MD, PhD, Named Chief Clinical Research Officer, Associate Cancer Center Director for Clinical Research at Yale Cancer Center

  • PDF Version

• Winter Vol 12 No 1 (January)
  • New Alliance Committee Leadership
    Alliance Leukemia Committee Co-Chairs
    Alliance Symptom Intervention Vice-Chairs
  • Spotlight on Alliance Trials
    Alliance A082002 - Non-Small Cell Lung Cancer
    Alliance A032002 - Metastatic Urothelial Cancer
    Alliance A211901 - Smoking Cessation Interventions
  • Alliance Research Spotlight | Recap 2021 ASH Meeting
  • Alliance Foundation Funding Opportunity

  • Alliance in the News
    Alliance A041702 | NCI Sponsored Trial of Uproleselan in Older, Newly Diagnosed AML Patients Fit for Intensive Chemotherapy Completes Enrollment of Phase 2 Portion Ahead of Schedule
    Alliance A041202 | Jennifer A. Woyach, MD, Discusses Previous Results of the A041202 Trial Examining Ibrutinib Regimens in CLL
    Inaugural ASCO Plenary Series Session [AFT-39 PRO-TECT] | Digital Symptom Monitoring Using Patient-Reported Data Helps Improve Symptom Control and Physical Function of Patients During Cancer Treatment
    CALGB/Alliance AML Trials 1986-2016 | AML in Younger Black AYAs Molecularly Distinct, Associated with Shorter Survival
    CALGB 40603 | CALGB 40603 (Alliance): Long-Term Outcomes and Genomic Correlates of Response and Survival After Neoadjuvant Chemotherapy With or Without Carboplatin and Bevacizumab in Triple-Negative Breast Cancer
    CALGB 89803 | Diet- and Lifestyle-Based Prediction Models to Estimate Cancer Recurrence and Death in Patients With Stage III Colon Cancer (CALGB 89803/Alliance)

  • PDF Version

• Press Release
  (December) Breast Cancer Patients Who Interrupted Endocrine Therapy to Pursue Pregnancy Did Not Experience Worse Recurrence Rates (POSITIVE Trial)

• 2021
• Winter Vol 11 No 3 (December)
  • Spotlight on Alliance Trials | Recap 2021
    Alliance A032002 - Metastatic Urothelial Cancer
    Alliance A211901 - Smoking Cessation Interventions
    Alliance A021901 - Bronchial Neuroendocrine Tumors
    Alliance A051902 - Peripheral T-Cell Lymphomas
    Alliance A222001 - Reducing Hot Flashes in Men
    Alliance A031902 - Metastatic Castration-Resistant Prostate Cancer
    Alliance A011801 - HER2-Positive Breast Cancer (CompassHER2)
  • Alliance/AFT/Foundation Holiday Closures
  • Alliance in the News
    Alliance Phase I/II Study Shows Increased Progression-Free Survival for Patients with Relapsed/Refractory Multiple Myeloma Who Received Ixazomib (Ninlaro®) in Combination with Pomalidomide and Dexamethasone
    

    Improving Patient-Centered Communication in Breast Cancer: Randomized Controlled Trial of SharES

    Results of Bevacizumab-Chemotherapy Combinations for Patients with Advanced Urothelial Cancer - Expert Commentary

    Study Reveals Underrepresentation of AYA Hispanic Patients in a Large ALL Clinical Trial

    Moving Beyond One Size Fits All for T-Cell Lymphoma

    Breast Cancer Study is First to Jointly Open at all Advocate Aurora Health Community Cancer Clinics

    Matched Cohort Study of Germline BRCA Mutation Carriers with Triple Negative Breast Cancer in Brightness

    Survival Similar for Younger and Older Patients with Metastatic Colorectal Cancer, Study Finds

  • PDF Version

• Fall Vol 11 No 2 (September)
  • Message From the Group Chair - Monica M. Bertagnolli, MD
  • Registration Now Open - Alliance 2021 Fall Virtual Group Meeting
  • Alliance Expresses Gratitude to Committee Chairs Ending Terms
  • Alliance Welcomes New Committee Leaders
  • NCI NCORP Honors Two Alliance Members
  • Spotlight on Alliance Trials
    Ten Currently Active Alliance Cancer Control Program/NCORP Research Base Trials
    Alliance A171901 - Lung Cancer
    Alliance A191901 - Endocrine Therapy Adherence
    Alliance A211102 - Testing for Atypia
    Alliance A211601 - Mammographic Breast Density
    Alliance A221702 - Axillary Reverse Mapping
    Alliance A221805 - Peripheral Neuropathy
    Alliance A222001 - Reducing Hot Flashes in Men
    Alliance A231601CD - Improving Surgical Care/Outcomes (OPIT-Surg)
    Alliance A231701CD - Shared Breast Cancer Surgery Decision Making
    Alliance A231901CD - Patient-Centered Communication in Breast Cancer
    
    Four Recently Activated Alliance NCTN Trials
    Alliance A021901 - Bronchial Neuroendocrine Tumors
    Alliance A051902 - Peripheral T-cell Lymphoma
    Alliance A031902 - Metastatic Castration-Resistance Prostate Cancer  (CASPAR)
    Alliance A011801 - HER2-Positive Breast Cancer (CompassHER2)
    
    Closed to Accrual: Alliance A221505 (RT CHARM)
  • Alliance Funding Opportunities
    Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods Award
  • Alliance in the News
    Patient Perspective in Clinical Trials – Alliance Patient Advocate Julie Krause Interview
    Randomized Phase II Study of PET Response–Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial
    Patient Perspective on Clinical Trials - Alliance Patient Advocate Julie Krause
    Impact of the COVID-19 Pandemic on Clinical Trials
    Combining Tumor Deposits with the Number of Lymph Node Metastases to Improve the Prognostic Accuracy in Stage III Colon Cancer: A Post Hoc Analysis of the CALGB/SWOG 80702 Phase III Study (Alliance)
    New ECU, Vidant Partnership Provides Access to Clinical Trials for Rare Cancers
    Celecoxib Provides No Survival Benefit for Patients with Stage III Colon Cancer
    Disparities in Older Adult Accrual to Cancer Trials: Analysis from the Alliance for Clinical Trials in Oncology (A151736)
  • PDF Version

• Spring Vol 11 No 1 (May)
  • Message From Alliance Leadership
    Message From the Group Chair - Monica M. Bertagnolli, MD
    Message From the Group Statistician - Sumithra J. Mandrekar, PhD
  • Grant Expands Clinical Trial Reach to Kansas' Rural Communities
    by Gary Doolittle, MD, Priyanka Sharma, MD, and Jaime Wagner, DO, FACOS, FACS
  • Alliance Activates 11 New Trials Over the Past Year
    Alliance A031902 - Prostate Cancer
    Alliance A011801 - Breast Cancer
    Alliance A031901 - Bladder Cancer
    Alliance A191901 - Endocrine Therapy Adherence
    Alliance A021804 - Neuroendocrine Cancer
    Alliance A071702 - Recurrent Glioblastoma
    Alliance A171901 - Non-small Cell Lung Cancer
    Alliance A091902 - Angiosarcoma
    Alliance A021806 - Resectable Pancreatic Cancer
    Alliance A081801 - Non-small Cell Lung Cancer
    Alliance A221805 - Peripheral Neuropathy Prevention/Colorectal Cancer
  • Alliance/AFT at 2021 ASCO
  • Alliance Funding Opportunities
    Alliance Scholar Awards
    Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods Award
  • Alliance Spring Virtual Group Meeting Recap
    Richard L. Schilsky CALGB Achievement Award
    Alliance Leadership Appointments
    Alliance for Clinical Trials in Oncology Foundation Special Project Allocation Awards
  • Alliance in the News
    New Operating Standard: mCODE Collaboration Is Bringing Uniformity to EHR Data
    
    Trials Explore Whether Endocrine Therapy Can Delay or Avert Surgery in Low-Risk DCIS
    

    Neoadjuvant Endocrine Therapy Use in Early Stage Breast Cancer During the COVID-19 Pandemic

    The Alliance Trial A031801 - RadiCal a Trial of Radium-223 in Patients with Renal Cell Carcinoma, - Rana McKay

    A Noticeable Absence

    CASPAR (Alliance A031902): A Randomized, Phase III Trial of Enzalutamide (ENZ) with Rucaparib (RUCA)/Placebo (PBO) as a Novel Therapy in First-Line Metastatic Castration-Resistant Prostate Cancer (MCRPC)

    Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients with Stage III Colon CancerThe CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial

    New Data Support Preoperative Chemoradiation Regimen for Borderline Resectable Pancreatic Cancer

    Electronic Geriatric Assessment: Is It Feasible in a Multi-Institutional Study That Included a Notable Proportion of Older African American Patients? (Alliance A171603)
    
    How did a multi-institutional trial show feasibility of electronic data capture in older patients with cancer? Results From a Multi-Institutional Qualitative Study (Alliance A171902)
    
    Randomized Phase III Trial of Gemcitabine and Cisplatin With Bevacizumab or Placebo in Patients With Advanced Urothelial Carcinoma: Results of CALGB 90601 (Alliance)

  • PDF Version

• Press Releases
  (December): Alliance for Clinical Trials in Oncology Phase I/II Study Shows Increased Progression-Free Survival for Patients with Relapsed/Refractory Multiple Myeloma Who Received Ixazomib (Ninlaro®) in Combination with Pomalidomide and Dexamethasone
  (October): Alliance Foundation Trials Opens Its First Gynecological Cancer Study
  (June): Sanofi Partnering with Leading Academic Cooperative Groups to Study Amcenestrant in the Adjuvant Setting for Patients with Estrogen Receptor-Positive Breast Cancer

• 2020
• Fall Vol 10 No 2 (December)
  • Message From the Group Chair - Monica M. Bertagnolli, MD
  • Alliance Investigators Work to Bring Practice-Changing Treatment Through Registration Trials
    Alliance A011801 - HER2+ Breast Cancer
    Alliance A021502 - Colon Cancer
    Alliance A021602 - Neuroendocrine Tumors
    Alliance A041701 - Acute Myeloid Leukemia
  • Alliance Announcements
    Alliance Appoints New Alliance Health Disparities Committee Chair - Lucile L. Adams-Campbell
    Alliance Imaging Committee Expands to Include New Subcommittee on Theranostics
    Recap: Alliance/AFT Abstracts at 2020 SABCS Meeting
    Recap: Alliance/AFT Abstracts at 2020 ASH Meeting
  • New Trials Alert
    Alliance A191901 - Support for Patients with Breast Cancer
    Alliance A021804 - Advanced Neuroendocrine Cancer
    Alliance A031901 - Metastatic Urothelial Carcinoma
    Alliance A071702 - Somatically Hypermutated Recurrent Glioblastoma
  • Closed to Accrual: Alliance A011502 (ABC Trial)
  • Alliance in the News
    Precision Treatment Advances Improve Survival in Women with Aggressive HER2+ Breast Cancer
    Black Race an Independent Predicator of Poor Survival Among Young Adults with AML
    Ohio State Creates Clara D. Bloomfield Center for Leukemia Outcomes Research
    American Cancer Society Announces New Members and Officers of Board of Directors
  • PDF Version
• Fall Vol 10 No 1 (October)
  • Alliance Activates New Trials, Enrolls Participants in Midst of COVID-19 Pandemic (snapshots)
    Alliance A171901 - Advanced non-small cell lung cancer
    Alliance A091902 - Angiosarcoma
    Alliance A021806 - Resectable pancreatic cancer
    Alliance A081801 - Non-small cell lung cancer
    Alliance A221805 - Peripheral neuropathy/colorectal cancer
    Alliance A151804 - National biorepository for immune-related adverse events
    Alliance A031803 - Invasive bladder cancer
  • Alliance - COVID-19 Updates and Resources (Alliance members)
  • Who We Are - Defining, Understanding All Four Distinct Alliance Entities
  • 2020 Alliance Fall Virtual Group Meeting Convenes Nov 4-7
  • Recent Alliance-related News & Publications
    Alliance Appoints Electra D. Paskett PhD Cancer Control Program Director, PI of Alliance NCORP Research Base
    ASCO Highlights Alliance Investigators
    Recap :: 2020 Alliance/ASCO Abstracts
    Alliance Researchers Identify Gene Variant Linked to Drug-Induced Hypertension from Bevacizumab
    What Happened to the US Cancer Cooperative Groups? A Status Update Ten Years After the Institute of Medicine Report
    The National Clinical Trials Network and the Cooperative Groups: The Road Not Taken
  • PDF Version

• 2019
• Winter Vol 9 No 4 (December)
  • Building Community Trust to Grow Underrepresented Minority Clinical Trial Participation in Southeastern Wisconsin
    Alliance Principal Investigator Perspectives - Tina W. F. Yen, MD, MS, Froedtert and the Medical College of Wisconsin LAPS
  • The Times They Are a-Changin'
    Alliance Transplant and Cell Based Therapies Committee - Miguel-Angel Perales, MD
  • Lessons Learned: Research Implementation Strategies for Community Based Clinics Participating in Clinical Trials
    Alliance Health Disparities Committee - Courtney Chun, University of Hawaii Cancer Center
  • 2019 Alliance/ASH Abstracts
  • 2019 Alliance/SABCS Abstracts
  • Spotlight on Alliance Trials Activated in 2019
  • Alliance Foundation Special Project Allocation
  • Recap: 2019 Alliance Fall Group Meeting | November 7-9
  • Happy Holidays from Alliance
  • PDF Version

• Fall Vol 9 No 3 (November)
  • Message From the Group Statistician - Sumithra J. Mandrekar, PhD
    Leveraging Statistical, Methodological Research to Advance Alliance Initiatives
  • Optimizing Clinical Trials to Improve Anti-Cancer Immune Response
    Alliance Immuno-Oncology Committee - David Kozono, MD, PhD, Andrew B. Nixon, PhD, Elizabeth Mittendorf, MD, PhD
  • 2019 Alliance Fall Group Meeting Convenes This Week - November 7-9
    Schedule, Agendas, E-Posters, Registration
  • Spotlight on Alliance Trials
    Alliance A021703 - Metastatic colorectal cancer
    Alliance A071701 - Genetic testing in brain metastases
    Alliance A071801 - Metastatic brain cancer
    Alliance A221702 - Axillary reverse mapping
  • PDF Version

• Summer Vol 9 No 2 (July)
  • Message From the Group Chair - Monica M. Bertagnolli, MD
  • PI Perspective: Alliance Health Outcomes Committee
    Michelle Naughton, PhD and Amylou Dueck, PhD (Co-Chairs)
    Jackie Lafky, MS (Program Manager)
  • Changing the Guard: Director and PI, Alliance Central Protocol Operations Program
    Gin F. Fleming, MD, FASCO and Olwen Hahn, MD
  • Recent Alliance Protocol Activations
  • Spotlight on Alliance Trials
    Alliance A091802 - Cutaneous squamous cell carcinoma
    Alliance A041701 - Chronic myeloid leukemia
    Alliance A031704 - Advanced renal cell cancer
    Alliance A031702 - Rare genitourinary tumors
  • ICAREdata | Integrating Clinical Trials and Real World Endpoints
  • Adding Value to the Alliance Clinical Trial Process
    Alliance Patient Advocate Committee
  • Announcements
    -- Alliance Joins with ASCO, CancerLinQ and The MITRE Corporation to Publish Initial Set of Common Cancer Data Standards and Specifications Comprising mCODE (VIDEO))
    -- Recap: Alliance and Alliance Foundation Trials at 2019 ASCO
    -- Renewed NCI Investigational Agent Accountability Record Forms (DARFs)
    -- Call for Nominations + Applications: 2019/2020 Alliance Awards + Honors
    -- Alliance Appoints New Committee Chairs
  • Alliance in the News
    -- GNS Healthcare Chosen to Present Discovery of New Clinical Predictors of Overall Survival in Metastatic Colorectal Cancer at ESMO 2019 in Collaboration with the Alliance for Clinical Trials in Oncology
    -- mCODE Improves EHR Data Standardization for Cancer Research
    -- First Patient Dosed in Phase III Study of E-Selectin Antagonist Uproleselan in AML (Alliance A041701)--ASCO 2019: CALGB 90601 (Alliance): Randomized, Double-blind, Placebo-controlled Phase III Trial Comparing Gemcitabine and Cisplatin with Bevacizumab or Placebo in Patients with Metastatic Urothelial Carcinoma
    --'Magic Mouthwash' Little Help for Radiation-Induced Mucositis (Alliance A221304)
    -- Magic mouthwash effective treatment for mouth sore pain caused by radiation therapy (Alliance A221304)
    -- Mouthwashes Show Promise in Reducing Chemo-Related Oral Mucositis Pain (Alliance A221304)
    -- Giving Drugs before Surgery Lowers the Risk of Prostate Cancer Returning (CALGB 90203)
    -- Study: Identifying colorectal cancer subtypes could improve treatment (CALGB/SWOG 80405)
    -- The Fight to Save the Bladder Turns to Genomics (Alliance A031701)
  • PDF version
• Winter Vol 9 No 1 (March)
  • Registration Now Open - 2019 Alliance Spring Group Meeting
    New Contact for Group Meeting Logistics
  • Professional Responsibility at the Forefront | Where Alliance Stands on Conflict of Interest
    James Bearden, MD and Jeffery Crawford, MD
    2019 Conflict of Interest (COI) Solicitation
  • Message From the Group Statistician Sumithra J. Mandrekar, PhD
  • Recent Alliance Protocol Activations
    Alliance A231602CD - Financial toxicity (blood cancers)
    Alliance A221701 - Oral stomatitis
    Alliance A041702 - Chronic lymphocytic leukemia
    Alliance A041703 - Acute lymphoblastic leukemia
  • Guest Columnists
    Disparities Corner: Shoshana Rosenberg, ScD, MPH and Suzanne George, MD - Addressing Disparities in Care and Outcomes in Adolescent and Young Adult Cancer Patients
    Zoneddy Dayao, MD PI, University of New Mexico Comprehensive Cancer Center - Reality of Bringing Clinical Trials to the Medically Underserved
  • Announcements
    Regulatory Column | NIH Single IRB (sIRB) Implementation
    New Monthly IPEC Performance Updates for Data Submission Timeliness
    Call for Papers to Honor and Remember Dr. Arti Hurria
  • Alliance in the News
    Treatment for Children with Leukemia Also Effective for Adolescents, Young Adults
    Exercise & Weight Loss to Prevent Breast Cancer Recurrence
    Celebrating NCORP Women in Science
    New Leukemia Drug is More Effective and Easier to Use
  • PDF version

• 2018
• Winter Vol 8 No 6 (December)
  • Message From The Group Chair
    Happy Holidays!
  • Guest Columnists
    Jeffrey A. Bogart, MD - Value of Local Therapy in an Era of Unprecedented Scientific Advancement
    Rena M. Conti, PhD and Gabriela Gracia, PhD - Treatment-Related Financial Difficulties: Patient and Practice Perspective
    Disparities Corner: Evan Kovac, MD, CM, FRCSC - Prostate Cancer Disparities in Minority Men, Challenges in Accruing to Clinical Trials
    Making Connections: Jennifer Dill, CCRP - Alliance Clinical Research Professionals At The Forefront
  • Announcements
    Recently Activated Trials
    Call for Abstracts: Amerian College of Surgeons Quality and Safety Conference
  • In Memoriam
    Arti Hurria, MD, FASCO - Leader in Geriatric Oncology
  • PDF Version
• Fall Vol 8 No 5 (October)
  • Spotlight on Fall Group Meeting
    New Ideas, Promising Prospects Expected When Meeting Convenes November 1-3
    Helpful Tips for Navigating the Group Meeting
  • Message From the Group Statistician
    Alliance Statistics and Data Center: On the Cutting Edge of Statistical, Methodological Research
  • Guest Columnists
    Eva A. May, MBA - When Designing a Clinical Trial, Think Like a Marketing Manager
    Thomas C. Shea, MD - How We've Thrived in a "New" Marriage
  • Announcements
    Recently Activated Trials
    Six Investigators Win Funding Awards from Cancer Control and Cancer Care Delivery Research Programs
  • In Memoriam 
    David Sugarbaker, MD - Renowned Thoracic Surgeon
  • #Did You Know
    About Deadlines for Alliance Abstracts
    About Alliance Foundation Trials
  • PDF Version
• Summer Vol 8 No 4 (August)
  • Spotlight on Trials
    Three New Alliance Protocol Activations
    Update - Two Trials Focus on Rare Population Subsets: Alliance A091302 and Alliance A091305
  • Alliance in the News
    From Cattle Rancher to ASCO President: Monica Bertagnolli, MD, on her motivations and goals
    Geoffrey Uy, MD, to Lead Pivotal Phase III Trial for Patients with Acute Myeloid Leukemia (AML)
    Comparative Effectiveness of Decision Aids in Diverse Populations with Prostate Cancer (Alliance 191402CD)
    Associations of Artificially Sweetened Beverage Intake with Disease Recurrence and Mortality in Colon Cancer (CALGB 89803)
  • Guest Columnists
    Richard M. Stone, MD - Intergroup Collaboration Emphasized in Era of Many New Drugs in Leukemia
    Alison Conlin, MD - Cancer Research in the Beautiful Pacific Northwest
    Disparities Corner | Haejin In, MD, MBA, MPH, FACS - Identifying Gastric Cancer Risk Through Cancer Disparities
  • Announcements
    Call for Nominations: Charles G. Moertel Lecturer
    Call for Abstracts: CRPs and Oncology Nurses
    In Memoriam: Alliance Patient Advocates - Robert Harrison and Hank Porterfield
  • Fall Group Meeting
    Schedule Now Available
    Registration Opens Late August
  • #Did You Know
    About Meeting Materials from May 2018 (public site) or (member site)
    About Deadlines for Alliance Abstracts
    About Alliance Foundation Trials
  • PDF Version
• Summer Vol 8 No 3 (June)
  • Spotlight on Trials
    Recent Alliance Protocol Activations
    Results from Alliance N1048 May Influence Future Treatment
    What's New in Alliance Cancer Care Delivery Research
    Sidedness as Key Indicator in Metastatic Colorectal Cancer (CALGB 80405)
    Alliance in the News
  • Guest Columnist
    Ann L. Oberg, MD - SDC Update
  • Announcements
    Hats Off! Giants in Cancer Care
    Operative Standards for Cancer Surgery
    NIH Public Access Policy Applies for Alliance Manuscripts
  • Alliance at 2018 ASCO Recap
  • Spring Group Meeting Recap
    Session Videos Now Available
    New Meeting App Stats
  • #Did You Know
    About Alliance Roster Updates
    About Deadlines for Alliance Abstracts
    About Corrections in OPEN
    About Alliance Foundation Trials
  • PDF Version
• Spring Vol 8 No 2 (April)
  • Spotlight on Trials
    Recent Alliance Protocol Activations
    Alliance Myeloma Committee
    New DCIS Special Study
    Work from Inaugural CCP Junior Faculty Award Recipients
  • Alliance in the News
  • Group Meeting Highlights
  • Guest Columnists
    Eileen O'Reilly, MD and Jeffrey Meyerhardt, MD - Next Generation Approaches
  • Announcements
  • Steven Piantadosi, MD, PhD - New Associate Group Chair for Strategic Initiatives and Innovation
  • Revisiting the Alliance Conflict of Interest Policy
  • Will Conversion to CTCAE v5 Impact Alliance Trial?
  • New Member Join Alliance Patient Advocate Committee
  • RFP: Aflac Archie Bleyer Young Investigator Award
  • In Memoriam: James F. Holland, MD and Karen Durham
  • PDF Version
• Winter Vol 8 No 1 (February)
  • Spotlight on Trials:
    Recent Alliance Protocol Activations
    Alliance Experimental Therapeutics and Rare Tumor Committee
    Alliance Abstracts at Annual Meetings
  • Alliance in the News
  • Message From the Group Statistician
  • Guest Columnists
    Ellis Levine, MD - The Good Fight
    John P. Leonard, MD - The Argument for Simplicity in Clinical Trials During an Era of Precision Medicine
    Patty Spears and Coleen Crespo, MIS - Advocating to Measure What Matters to Patients
  • Alliance Spring Group Meeting Registration Now Open
    Investigators Panel - Clinical Trial Obstacles and Overcoming Them
  • Announcements
    New Members Join Alliance Patient Advocate Committee
    Alliance/ACS CRP to Present Clinical Trials Training Course at SSO Annual Meeting
    Call for Abstracts: Alliance CRP/Oncology Nursing Committees
    RFP: Aflac Archie Bleyer Young Investigator Award
    Did You Know? Alliance Website Tips
  • PDF Version
• 2017
• Winter Vol 7 No 5 (December)
  • Recap: Alliance Fall Group Meeting
    Message From the Group Chair and Group Statistician
  • Spotlight on Trials:
    Results From Alliance Trial Lead to U.S. FDA Approval of Extended Indication (CABOSUN - Alliance A031203)
    Recent Alliance Protocol Activations
    Ongoing Trials - Alliance A011104 and Alliance A011106
  • Alliance at ASH 2017
  • Alliance at SABCS 2017
  • Announcements: Awards + Honors
    Alliance Most Significant Manuscripts
    Alliance Scholar Award
  • Announcements: General
    Service Recognition: Alliance Patient Advocate Committee Members
    In Memoriam:
      Jack Whelan
      Patrick Gavin, RPh
      Jimmie C. Holland, MD
  • Alliance/ASCO Abstract Submission Deadline
  • Featured Columns
    Meet the Alliance Executive Officers
    Alliance Disparities Committee Corner
    Did You Know? Alliance Website Tips
  • Holiday Closures
  • PDF Version
• Fall Vol 7 No 4 (October)
  • Alliance Fall Group Meeting Convenes
  • Spotlight on Trials: Recent Alliance Protocol Activations
  • Alliance in the News
  • Announcements: Awards
    Daniel J. Sargent, PhD, Memorial Fellowship in Innovative Clinical Trial Design and Methods
    Alliance Cancer Care Delivery Research Committee Pilot Project Award
    Alliance Cancer Control Program Pilot Project Award and Junior Investigator Award
  • Announcements: General
    New Alliance Investigator Course Successfully Introduced at Spring Meeting
    New Changes to CTMB Audit Guidelines
  • Featured Columns
    Alliance Disparities Committee Corner
    Focus on: Alliance/American College of Surgeon Clinical Research Program (ACS CRP)
  • Did You Know? Alliance Website Tips
  • Thanksgiving Closure
  • PDF Version
• Summer Vol 7 No 3 (August)
  • Spotlight on Alliance Trials
    CALGB (Alliance) 10603 | FDA Approves New Combination Treatment for AML
    Alliance 221208 | Managing Brain Radionecrosis (BeSt Trial) 
    Alliance A091202 | Intervention for Myxoid Liposarcoma
    Alliance A091305 | Rare Tumor Subset for Advanced Anaplastic Thyroid Cancer
  • In the News
  • Protocols
    Recent Alliance Protocol Activations
  • Alliance at ASCO 2017
  • Staff & Members
    Meet New Alliance Board of Directors and Executive Committee
    Meet New Alliance Leadership
    Alliance Members on the Move
  • Announcements
    What Alliance Members Need to Know About CTEP's New Registration and Credentialing Repository (RCR)
  • Featured Columns
    Alliance Breast Committee Member Survey
    Alliance Disparities Committee Corner
  • Did You Know? Alliance Website Tips
  • Alliance Mission: By the Words
  • PDF Version
• Winter Vol 7 No 1 (February)
  • Message From the Group Statistician
  • New Co-Chairs to Lead Alliance Cancer in the Elderly Committee
  • Alliance Leaders Assume New Posts
  • Protocols
    Recent Alliance Protocol Activations
  • Spotlight on Alliance Trials
    CALGB (Alliance) 100104 | Alliance Trial Results Lead to FDA Approval
    Alliance A021302 | Gastric Cancers
    Alliance A061402 | Solitary Plasmacytoma of the Bone
    Alliance A091302 | Hürtle Cell Thyroid Cancer
  • CRP Perspective (new recurring column)
    "A Rose (or Roger) By Any Other Name"
  • Staff & Members
    Meet New Alliance Leadership
    Alliance Members on the Move
    Call for Nominations: Alliance Respiratory Committee Co-Chair 
  • Member Services
    Undertanding Alliance Member Accrual Credits
    Understanding the Importance of CTEP-IAM Registration
  • CTMB Update
  • Did You Know? Alliance Website Tips
  • Alliance Mission: By the Words
  • PDF Version

• 2016
• Winter Vol 6 No 5 (December)
  • Message From the Group Chair
  • Daniel J. Sargent Alliance Memorial Service Video
  • Alliance Leaders Elected to ASCO Posts
  • Recent Alliance Protocol Activations
  • Meet New Alliance Leadership
  • New Alliance Staff
  • Alliance Names Most Notable, Original Manuscripts
  • Annual Alliance Research Awards
  • Recap: 2016 ASH Meeting
  • Learm more about NCI-Sponsored Precision Medicine Trials
  • New NCI Liaisons to Alliance Cancer Control Program
  • Alliance Institutional Best Practices Blog (member site)
  • Alliance Mission: By the Words
  • PDF Version
• Fall Vol 6 No 4 (October)
  • Registration Now Open for Alliance Fall Group Meeting
  • In Memoriam: Daniel J. Sargent, PhD
  • Four Investigators Receive Funding Through Alliance Cancer Control Program
  • Alliance Researcher Approved for $5.45M PCORI Funding Award
  • NCI Selects Alliance Researcher to Co-Chair CCDR Coordinating Committee
  • Results from NCCTG (Alliance) N107C Trial for Patients with Metastatic Brain Tumors
  • New Alliance Committee Leadership
  • Recent Alliance Protocol Activations
  • Did You Know? Three Alliance Website Tips
  • PDF Version
• Summer Vol 6 No 3 (August)
  • Two Leading Cancer Researchers to Co-Chair Alliance Breast Committee
  • Meet New Alliance Leaders
  • Greetings from Alliance Statistics and Data Center
  • Spotlight on Patient Advocacy: Resolution
  • What's New? Alliance Member Services Enhancement Task Force
  • Spotlight on Alliance Trials:
    NCCTG (Alliance) N0574
    
    Alliance A031203
    In the News:
    

    Alliance A011401
    CALGB/SWOG/Alliance 80405
  • Alliance On the Move:
    New Staff  
    Members Making Strides
  • Call for Nominations:
    Moertel Lecture  
    Alliance Community Oncology Committee Co-Chair  
    Alliance Prevention Committee Co-Chair
  • Did You Know? Four Alliance Website Tips
  • PDF Version
• Spring Vol 6 No 2 (May)
  • Alliance Convenes 2016 Spring Group Meeting May 12-14
  • Thirteen Years of Service for Co-Chairs of the Alliance Breast Committee
  • CALGB 10603 (RATIFY) Study Results in FDA Breakthrough Therapy Desgination
  • Alliance Welcomes New Staff
  • In Memoriam: Egbert C. Brown and Kathleen W. Rao, PhD, FACWG
  • Funding Opportunities: CCP Pilot Project  CCP Jr. Faculty Awards  CCDR Pilot Project
  • Alliance Foundation Award Opportunities: Richard L. Schilsky CALGB Achievement Award  Alliance Scholar Award
  • PDF Version
• Spring Vol 6 No 1 (March)
  • Alliance Researcher Approved for PCORI Award
  • Chicago 'Top Doctors'
  • Alliance CRP Committee Improves Training
  • Alliance Study to Assess Post RT Treatment Options
  • Reducing Cancer-related Fatigue Focus of Alliance Study
  • Recap: 2015 ASH Meeting
  • Did You Know? Searchable Alliance Pubs App
  • Positions Available: Alliance Breast Committee, Alliance Oncology Nursing Committee and Alliance Pharmacy Committee
  • Renewal of DARF + IR Forms
  • PDF Version

• 2015
• Winter Vol 5 No 6 (December)
  • Message From the Group Chair
  • First Targeted Therapy for Patients with High-Risk AML
  • Alliance, GNS Launch Big Data Initiative to Transform Metastatic Colorectal Cancer
  • Meet New Alliance Leadership
  • New Leadership, Staff in Alliance Statistics Unit
  • Alliance Data Management Unit Consolidation
  • Alliance Receives 'The Charlie Award' from CEO Roundtable on Cancer
  • Alliance Names Most Notable, Original Manuscripts
  • Annual Alliance Research Awards
  • Alliance Patient Advocate Committee Update
  • Alliance Mission: By the Words
  • PDF Version
• Fall Vol 5 No 5 (November)
  • Alliance Convenes 2015 Fall Group Meeting November 5-8
  • Introducing Alliance Foundation Trials, LLC (AFT)
  • Alliance Researchers Explore Use of Aspirin to Treat Breast Cancer
  • Deadlines for Upcomnig Alliance Abstracts
  • Four Investigators Receive Funding Awards from Alliance Cancer Control Program (updated)
  • New Study Chair Appointments | Alliance A071101
  • On the Move: Alliance Members + Welcome New Staff
  • PDF Version
• Fall Vol 5 No 4 (October)
  • AFT Launches New PALLAS Trial
  • Pivotal Alliance Thyroid Cancer Trials: A091302 and A091305
  • Alliance Researchers Approved for PCORI Awards
  • Meet the Alliance Member Services Enhancement Task Force
  • Edith Perez Steps Down as Vice Chair
  • CRP Resources Now Available
  • New CRP Breakout Sessions for Alliance Fall Group Meeting
  • Upcoming Pilot Project from the A-ONC Team
  • A-OCN Seeks GU Liaison
  • Alliance Hosts SOCRA Exam
  • Upcoming Conferences
  • PDF Version

• Summer Vol 5 No 3 (July)
• Spring Vol 5 No 2 (May)
• Winter Vol 5 No 1 (February)

• 2014
• Winter Vol 4 No 6 (December)
• Fall Vol 4 No 5 (October)
• Summer Vol 4 No 4 (July)
• Spring Vol 4 No 3 (May)
• Winter Vol 4 No 2 (February)
• Winter Vol 4 No 1 (January)

• 2013
• Winter Vol 3 No 9 (December)
• Fall Vol 3 No 8 (September)
• Summer Vol 3 No 7 (July/August)
• Summer Vol 3 No 6 (June)
• Spring Vol 3 No 5 (May)
• Spring Vol 3 No 4 (April)
• Spring Vol 3 No 3 (March)
• Winter Vol 3 No 2 (February)
• Winter Vol 3 No 1 (January)

• 2012
• Fall Vol 2 No 9 (October)
• Fall Vol 2 No 8 (September)
• Summer Vol 2 No 7 (July/August)
• Summer Vol 2 No 6 (June)
• Spring Vol 2 No 5 (May)
• Spring Vol 2 No 4 (April)
• Spring Vol 2 No 3 (March)
• Winter Vol 2 No 2 (February)
• Winter Vol 2 No 1 (January)

• 2011
• Winter Vol 1 No 5 (December)
• Fall Vol 1 No 4 (November)
• Fall Vol 1 No 3 (October)
• Fall Vol 1 No 2 (September)
• Summer Vol 1 No 1 (August)

In Memoriam: Daniel J. Sargent, PhD | Alliance Memorial Service Video (November 2016) | Celebration of Life Tribute Book (pdf)