Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods

The Alliance for Clinical Trials in Oncology Foundation is pleased to offer the Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods award for a one-year, non-renewable term.

The fellowship award honors the contributions of Dr. Sargent to the field of clinical cancer research. It is open to faculty or master's level statisticians (working with a senior faculty member) within the Alliance Statistics and Data Management Center (SDMC). Proposals must be closely tied to the research agenda of the Alliance and Alliance SDMC. The work proposed should address study design and/or data analysis approaches that are directly relevant to current challenges in the areas of cancer clinical trials. The proposal should address achieving innovation in one or more of the following areas: cancer clinical trial design, prognostic and predictive biomarkers, endpoints, trial conduct, and monitoring, analytical methods, and execution. The work should directly lead to a peer-reviewed publication or preliminary data for a grant proposal.

Dr. Larson is a biostatistician with an interdisciplinary background in the areas of statistical genetics, bioinformatics and computational biology. His research interests are motivated by the unique opportunities and challenges provided by high-dimensional molecular data in addressing outstanding questions about complex human phenotypes. He is a Senior Associate Consultant II-Research in the Division of Biomedical Statistics and Informatics in the Department of Quantitative Health Sciences and an Associate Professor of Biostatistics at the Mayo Clinic. He works collaboratively to improve understanding of a variety of complex diseases, including cardiovascular disease and cancer. Dr. Larson's long-term research goals involve empowering genomic studies through the integration of multiple sources of information. His proposal is entitled “Leveraging polygenic risk scores as prognostic markers in cancer outcomes.”


Past Fellowship Recipients

Paul J. Novotny, MS
- Assistant Professor, Biostatistics, Mayo Clinic 
Project: "Choice of Study Endpoints and Analysis Methods in Symptom Intervention Clinical Trials with Continuous Patient-Report Outcomes: A Monte Carlo Power Analysis and Application to Alliance CIPN and Hot Flash Clinical Trials"

David Zahrieh, PhD,
Assistant Professor, Health Sciences Research - Mayo Clinic 
Project: "Composite Response Endpoint to Evaluate Effectiveness of New Interventions for the Prevention of Oxaliplatin-induced Peripheral Neuropathy"

Vivien (Jun) Yin, PhD, Assistant Professor of Biostatistics, Associate Consultant, and Faculty Statistician - Mayo Clinic
"Individualized Patient Dosing in Phase I Clinical Trials Incorporating Patient-Reported Outcomes"