Alliance - Newsletters

Home > Newsletters

Newsletters

Alliance E-News is the official newsletter of the Alliance for Clinical Trials in Oncology. The periodic newsletter focuses on current information about the Alliance, its policies and procedures, group meetings and activities, and other topics of interest to Alliance members and others in the cancer research community.

2023

Fall Vol 13 No 6 (November)
- November is National Lung Cancer Awareness Month
- 2023 Alliance Fall Hybrid Group Meeting Convenes November 1-4
Fall Vol 13 No 5 (October)
- Press Release
  >> Alliance Study Shows Promise for Patients with Muscle-Invasive Carcinoma
  >> Alliance Presents Detailed Results from Phase III CABINET Pivotal Trial Evaluating Cabozantinib in Advanced Neuroendocrine Tumors at ESMO 2023
- 2023 Alliance Fall Hybrid Group Meeting Convenes November 1-4

Fall Vol 13 No 4 (September)
- #World Lymphoma Awareness Day: Three Alliance Lymphoma Trials Now Enrolling Participants
- New Trial Alerts
  Alliance A092105: Randomized phase 2 study of nivolumab and ipilimumab with or without cabozantinib in patients with advanced nasopharyngeal carcinoma that have progressed after platinum treatment and immunotherapy
  Study Chair: Glenn J. Hanna, MD | Activated: 09/18/2023
  Alliance A052101: A randomized phase 3 trial of continuous vs. intermittent maintenance therapy with zanubrutinib as upfront treatment in older patients with mantle cell lymphoma
  Study Chair: Anne Beaven, MD | Activated: 09/8/2023

Summer Vol 13 No 3 (August)
- New Trial Alert: Alliance EAY191-A6 A ComboMATCH Treatment Trial: FOLFOX in combination with binimetinib as 2nd line therapy for patients with advanced biliary tract cancers with MAPK pathway alterations
- Call for Nominations: 2023 Richard L. Schilsky CALGB Achievement Award
- Research Results
  Defining Priorities in Value-Based Cancer Care: Insights From the Alliance for Clinical Trials in Oncology National Cooperative Group Survey | Alliance Value in Cancer Care (ViCC) Subcommittee / Alliance Cancer Care Delivery Research Committee
- Press Release
  Alliance Study Shows Promising Results for Patients with Advanced Neuroendocrine Tumors

Summer Vol 13 No 2 (July)

Spring Vol 13 No 1 (May)

2022

Winter Vol 12 No 8 (December)
- Message From Alliance Leadership
  Interim Group Chair - Suzanne George, MD
  Group Statistician - Sumithra Mandrekar, PhD
- Group Chair Search - Alliance for Clinical Trials in Oncology
- New Alliance Committee Leadership
  Alliance Pathology Committee Chair
- Year In Review
  Spotlight on Recently Activated Alliance Trials
  Spotlight on Ongoing Alliance Trials
  Spotlight on Scientific Annual Meetings: 2022 SABCS & ASH
  Spotlight on Best Publications
  Spotlight on Alliance Trial Results
- Alliance/Alliance Entities Holiday Closures
- PDF
Fall Vol 12 No 7 (October)
- 2022 Alliance Fall Hybrid Group Meeting Convenes November 2-5
- Update on Alliance Participant Engagement Portal (PEP)
- November is National Lung Cancer Awareness Month
  A021901 (Bronchial Neuroendocrine Tumors)
  A081801 (ALCHEMIST chemo-IO)
  A082002 (Advanced Non-small Cell Lung Cancer)
  A151216 (ALCHEMIST)
  A171901 (Non-small Cell Lung Cancer in Older Adults)
- Spotlight on Alliance Trials
  *Ongoing Trials
  A011801 (COMPASS HER2 RD/Breast Cancer)
  A021602 (CABINET/Advanced Neuroendocrine Tumors)
  A021804 (Advanced Pheochromocytoma and Paraganglioma)
  A031902 (CASPAR/Metastatic Castration-resistant Prostate Cancer)
- Closed to Accrual (Alliance A031102 | TIGER)
- October ASCO Plenary Series (AFT-05 | PALLAS)
- PDF

Fall Vol 12 No 6 (September)

Summer Vol 12 No 5 (July)
- Nursing in the Modern Clinical Trials Era
  Lisa A. Kottschade, MSN, APRN, CNP - Chair, Alliance Oncology Nursing Committee
- July is National Sacroma and Bone Cancer Awareness Month
  A091902: Angiosarcoma
- Spotlight on Alliance Trials
  *Recently Activated Trials
  A221803 (Reducing Radiation Dermatitis) - Breast Cancer
  A091903 (Resected Mucosal Melanoma)
  *Ongoing Trials
  A011801 (COMPASS HER2 RD/Breast Cancer)
  A021602 (CABINET/Advanced Neuroendocrine Tumors)
  A021804 (Advanced Pheochromocytoma and Paraganglioma)
  A031902 (CASPAR/Metastatic Castration-resistant Prostate Cancer)
  A071702 (Somatically Hypermutated Recurrent Glioblastoma)
  A081801 (Non-small Cell Lung Cancer)
- Announcements
  Call for Nominations: Charles G. Moertel Lecture 2023
  2022 Alliance for Clinical Trials in Oncology Foundation Special Projects Allocation Awards
  Alliance Myeloma Committee Chair Appointment
  Alliance Board of Directors Approve New Program for Procedure-Based Therapy (PPBT)
  New Alliance Participant Engagement Portal to Launch Soon
- Alliance in the News
  Inequities in Alliance Acute Leukemia Clinical Trial and Biobank Participation: Defining Targets for Intervention
  Predictive Biomarkers of Overall Survival in Patients with Metastatic Renal Cell Carcinoma Treated with IFNα ± Bevacizumab: Results from CALGB 90206 (Alliance)
  
  Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy with Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)
  
  Biomarker Development: Bedside to Bench
- Alliance NCTN/NCORP/AFT at 2022 ASCO
- PDF
Spring Vol 12 No 4 (May)
- Remembering Jeff A. Sloan , PhD
- Alliance Spring Hybrid Group Meeting Convenes May 11-1 4
  Celebrating Our 10-Year Anniversary
- Clinical Trials Day - May 20, 2022
- Creating Surgical Standards to Improve Quality of Surgical Care
  Christina L. Roland, MD, MS - Chair, Alliance Cancer Care Standards Development Committee
  Kelly K. Hunt, MD - Director, Alliance/American College of Surgeons Clinical Research Program
- Alliance Data and Safety Monitoring Board: Who Are We and What Do We Do?
  Jeffrey J. Kirshner, MD, FACP, FASCO
  Director of Research, HOACNY and Chair, Alliance Data and Safety Monitoring Board
- Spotlight on Alliance Trials
  A071702 Somatically Hypermutated Recurrent Glioblastoma
  A171901 Non-small Cell Lung Cancer in Older Patients
- May is . . . National Bladder Cancer Awareness Month
  A031701 Muscle-invasive Bladder Cancer
  A031803 CG-unresponsive Non-muscle Invasive Bladder Cancer
  A031901 Metastatic Urothelial Carcinoma
  A032001 MAIN-CAV: Metastatic Urothelial Carcinoma
  A032002 ART: Platinum iIeligible/Refractory Metastatic Urothelial Cancer
- Alliance in the News
  ** A Wave of New Cancer Treatments Challenges Community Oncologists to Keep Up
  ** Geriatric Assessment for Older Adults Receiving Less Intensive Therapy for Acute Myeloid Leukemia: Report of CALGB 361101
  ** KDR Genetic Predictor of Toxicities Induced by Sorafenib and Regorafenib
  ** Sanofi Provides Update on Phase 2 Study Evaluating Amcenestrant in ER+/HER2- Advanced or Metastatic Breast Cancer
- PDF Version
Spring Vol 12 No 3 (March)
- Newly Implemented Changes Improve Alliance Audit Process
  Scott H. Okuno, MD - Chair, Alliance Audit Committee
  Kurombi Wade-Oliver, CCRP - Director, Alliance Quality Management and Audit Program
- Spotlight on Alliance Trials
  A022001 (Pancreatic Endocrine Tumors)
  A0 32001/MAIN CAV Study (Metastatic Urothelial Cancer)
- April is . . . National Cancer Control Month
  Cancer in the Older Adult | Cancer Care Delivery Research
  Health Disparities | Health Outcomes
  Prevention | Spymtom Intervention
- Alliance Foundation Funding Opportunity
- FY22 BIQSFP Funding Opportunity
- Alliance in the News
  ** Molecular, Clinical, and Prognostic Implications of PTPN11 Mutations in Acute Myeloid Leukemia
  ** Living with and Learning about Neuroendocrine Tumors: A Conversation with Dr. Jaydira Del Rivero
  ** Emerging Adjuvant Therapies in Renal Cell Carcinoma Post-ASCO GU ’22
  ** A Wave of New Cancer Treatments Challenges Community Oncologists to Keep Up
- PDF Version

Winter Vol 12 No 2 (February)
- Message From the Group Statistician - Sumithra J. Mandrekar, PhD
- Navigating Ethical Dilemmas, Guiding Investigators During the Conduct of Oncology Clinical Trials
  Fay J. Hlubocky, PhD, MA, and Jeffrey M. Peppercorn, MD, MPH - Co-Chairs, Alliance Ethics Committee
- Increased Skill Level, Training of Clinical Research Professionals Now Required to Meet Complexities of New Clinical Trials
  Jennifer Dill, CCRP - Chair, Alliance Clinical Research Professionals Committee
- Spotlight on Alliance Trials
  A211801 (BRCA-P Breast Cancer Prevention Study)
  
  March is . . .
- National Colorectal Cancer Awareness Month
  A021502: ATOMIC (DNA Mismatch Repair)
  A021703: SOLARIS (Vitamin D Supplementation)
  A221805 (Peripheral Neuropathy)
- National Kidney Cancer Awareness Month
  A301704: PDIGREE (Metastatic Untreated RCC)
  A031801: RadiCaL (Advanced RCC/Bone Metastasis)
- Alliance Foundation Funding Opportunity
- Alliance in the News
  Alliance A011502 | Aspirin Doesn’t Improve iDFS in Breast Cancer
  Alliance A021804 | NCI Clinical Trial Spotlight: Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer
  AFT-05 (PALLAS) | Safety of Adjuvant CDK4/6 Inhibitors During the COVID-19 Pandemic
  CALGB 90601 | Results of Bevacizumab-Chemotherapy Combinations for Patients with Advanced Urothelial Cancer - Expert Commentary
  Alliance A041202 | Anti-CD20 Monoclonal Antibodies for Chronic Lymphocytic Leukemia
  New Cancer Research | NCI Seeks to Develop Clinical Trial of MCED Tests
  Cancer Research Opinion | Congressional Inaction Harms Federally Funded Oncology Research and Our Patients: The Time for the Cancer Community to Act is Now
  Alliance Group Chair | Monica Bertagnolli, M.D., FACS joins Prevent Cancer Board of Directors
  Alliance Ethics Committee Co-Chair | Jeffrey Peppercorn, MD, MPH, Named Editor-in-Chief of JCO Oncology Practice
  Alliance Committee Co-Chair | Ian E. Krop, MD, PhD, Named Chief Clinical Research Officer, Associate Cancer Center Director for Clinical Research at Yale Cancer Center
- PDF Version

Winter Vol 12 No 1 (January)
- New Alliance Committee Leadership
  Alliance Leukemia Committee Co-Chairs
  Alliance Symptom Intervention Vice-Chairs
- Spotlight on Alliance Trials
  Alliance A082002 - Non-Small Cell Lung Cancer
  Alliance A032002 - Metastatic Urothelial Cancer
  Alliance A211901 - Smoking Cessation Interventions
- Alliance Research Spotlight | Recap 2021 ASH Meeting
- Alliance Foundation Funding Opportunity
- Alliance in the News
  Alliance A041702 | NCI Sponsored Trial of Uproleselan in Older, Newly Diagnosed AML Patients Fit for Intensive Chemotherapy Completes Enrollment of Phase 2 Portion Ahead of Schedule
  Alliance A041202 | Jennifer A. Woyach, MD, Discusses Previous Results of the A041202 Trial Examining Ibrutinib Regimens in CLL
  Inaugural ASCO Plenary Series Session [AFT-39 PRO-TECT] | Digital Symptom Monitoring Using Patient-Reported Data Helps Improve Symptom Control and Physical Function of Patients During Cancer Treatment
  CALGB/Alliance AML Trials 1986-2016 | AML in Younger Black AYAs Molecularly Distinct, Associated with Shorter Survival
  CALGB 40603 | CALGB 40603 (Alliance): Long-Term Outcomes and Genomic Correlates of Response and Survival After Neoadjuvant Chemotherapy With or Without Carboplatin and Bevacizumab in Triple-Negative Breast Cancer
  CALGB 89803 | Diet- and Lifestyle-Based Prediction Models to Estimate Cancer Recurrence and Death in Patients With Stage III Colon Cancer (CALGB 89803/Alliance)
- PDF Version
Press Release
(December) Breast Cancer Patients Who Interrupted Endocrine Therapy to Pursue Pregnancy Did Not Experience Worse Recurrence Rates (POSITIVE Trial)

2021
Winter Vol 11 No 3 (December)
- Spotlight on Alliance Trials | Recap 2021
  Alliance A032002 - Metastatic Urothelial Cancer
  Alliance A211901 - Smoking Cessation Interventions
  Alliance A021901 - Bronchial Neuroendocrine Tumors
  Alliance A051902 - Peripheral T-Cell Lymphomas
  Alliance A222001 - Reducing Hot Flashes in Men
  Alliance A031902 - Metastatic Castration-Resistant Prostate Cancer
  Alliance A011801 - HER2-Positive Breast Cancer (CompassHER2)
- Alliance/AFT/Foundation Holiday Closures
- Alliance in the News
  Alliance Phase I/II Study Shows Increased Progression-Free Survival for Patients with Relapsed/Refractory Multiple Myeloma Who Received Ixazomib (Ninlaro®) in Combination with Pomalidomide and Dexamethasone
  
  Improving Patient-Centered Communication in Breast Cancer: Randomized Controlled Trial of SharES
  
  Results of Bevacizumab-Chemotherapy Combinations for Patients with Advanced Urothelial Cancer - Expert Commentary
  
  Study Reveals Underrepresentation of AYA Hispanic Patients in a Large ALL Clinical Trial
  
  Moving Beyond One Size Fits All for T-Cell Lymphoma
  
  Breast Cancer Study is First to Jointly Open at all Advocate Aurora Health Community Cancer Clinics
  
  Matched Cohort Study of Germline BRCA Mutation Carriers with Triple Negative Breast Cancer in Brightness
  
  Survival Similar for Younger and Older Patients with Metastatic Colorectal Cancer, Study Finds
- PDF Version

Fall Vol 11 No 2 (September)
- Message From the Group Chair - Monica M. Bertagnolli, MD
- Registration Now Open - Alliance 2021 Fall Virtual Group Meeting
- Alliance Expresses Gratitude to Committee Chairs Ending Terms
- Alliance Welcomes New Committee Leaders
- NCI NCORP Honors Two Alliance Members
- Spotlight on Alliance Trials
  Ten Currently Active Alliance Cancer Control Program/NCORP Research Base Trials
  Alliance A171901 - Lung Cancer
  Alliance A191901 - Endocrine Therapy Adherence
  Alliance A211102 - Testing for Atypia
  Alliance A211601 - Mammographic Breast Density
  Alliance A221702 - Axillary Reverse Mapping
  Alliance A221805 - Peripheral Neuropathy
  Alliance A222001 - Reducing Hot Flashes in Men
  Alliance A231601CD - Improving Surgical Care/Outcomes (OPIT-Surg)
  Alliance A231701CD - Shared Breast Cancer Surgery Decision Making
  Alliance A231901CD - Patient-Centered Communication in Breast Cancer
  
  Four Recently Activated Alliance NCTN Trials
  Alliance A021901 - Bronchial Neuroendocrine Tumors
  Alliance A051902 - Peripheral T-cell Lymphoma
  Alliance A031902 - Metastatic Castration-Resistance Prostate Cancer (CASPAR)
  Alliance A011801 - HER2-Positive Breast Cancer (CompassHER2)
  
  Closed to Accrual: Alliance A221505 (RT CHARM)
- Alliance Funding Opportunities
  Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods Award
- Alliance in the News
  Patient Perspective in Clinical Trials – Alliance Patient Advocate Julie Krause Interview
  Randomized Phase II Study of PET Response–Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial
  Patient Perspective on Clinical Trials - Alliance Patient Advocate Julie Krause
  Impact of the COVID-19 Pandemic on Clinical Trials
  Combining Tumor Deposits with the Number of Lymph Node Metastases to Improve the Prognostic Accuracy in Stage III Colon Cancer: A Post Hoc Analysis of the CALGB/SWOG 80702 Phase III Study (Alliance)
  New ECU, Vidant Partnership Provides Access to Clinical Trials for Rare Cancers
  Celecoxib Provides No Survival Benefit for Patients with Stage III Colon Cancer
  Disparities in Older Adult Accrual to Cancer Trials: Analysis from the Alliance for Clinical Trials in Oncology (A151736)
- PDF Version

Spring Vol 11 No 1 (May)
- Message From Alliance Leadership
  Message From the Group Chair - Monica M. Bertagnolli, MD
  Message From the Group Statistician - Sumithra J. Mandrekar, PhD
- Grant Expands Clinical Trial Reach to Kansas' Rural Communities
  by Gary Doolittle, MD, Priyanka Sharma, MD, and Jaime Wagner, DO, FACOS, FACS
- Alliance Activates 11 New Trials Over the Past Year
  Alliance A031902 - Prostate Cancer
  Alliance A011801 - Breast Cancer
  Alliance A031901 - Bladder Cancer
  Alliance A191901 - Endocrine Therapy Adherence
  Alliance A021804 - Neuroendocrine Cancer
  Alliance A071702 - Recurrent Glioblastoma
  Alliance A171901 - Non-small Cell Lung Cancer
  Alliance A091902 - Angiosarcoma
  Alliance A021806 - Resectable Pancreatic Cancer
  Alliance A081801 - Non-small Cell Lung Cancer
  Alliance A221805 - Peripheral Neuropathy Prevention/Colorectal Cancer
- Alliance/AFT at 2021 ASCO
- Alliance Funding Opportunities
  Alliance Scholar Awards
  Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods Award
- Alliance Spring Virtual Group Meeting Recap
  Richard L. Schilsky CALGB Achievement Award
  Alliance Leadership Appointments
  Alliance for Clinical Trials in Oncology Foundation Special Project Allocation Awards
- Alliance in the News
  New Operating Standard: mCODE Collaboration Is Bringing Uniformity to EHR Data
  
  Trials Explore Whether Endocrine Therapy Can Delay or Avert Surgery in Low-Risk DCIS
  
  Neoadjuvant Endocrine Therapy Use in Early Stage Breast Cancer During the COVID-19 Pandemic
  
  The Alliance Trial A031801 - RadiCal a Trial of Radium-223 in Patients with Renal Cell Carcinoma, - Rana McKay
  
  A Noticeable Absence
  
  CASPAR (Alliance A031902): A Randomized, Phase III Trial of Enzalutamide (ENZ) with Rucaparib (RUCA)/Placebo (PBO) as a Novel Therapy in First-Line Metastatic Castration-Resistant Prostate Cancer (MCRPC)
  
  Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients with Stage III Colon CancerThe CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial
  
  New Data Support Preoperative Chemoradiation Regimen for Borderline Resectable Pancreatic Cancer
  
  Electronic Geriatric Assessment: Is It Feasible in a Multi-Institutional Study That Included a Notable Proportion of Older African American Patients? (Alliance A171603)
  
  How did a multi-institutional trial show feasibility of electronic data capture in older patients with cancer? Results From a Multi-Institutional Qualitative Study (Alliance A171902)
  
  Randomized Phase III Trial of Gemcitabine and Cisplatin With Bevacizumab or Placebo in Patients With Advanced Urothelial Carcinoma: Results of CALGB 90601 (Alliance)
- PDF Version

Press Releases
(December): Alliance for Clinical Trials in Oncology Phase I/II Study Shows Increased Progression-Free Survival for Patients with Relapsed/Refractory Multiple Myeloma Who Received Ixazomib (Ninlaro®) in Combination with Pomalidomide and Dexamethasone
(October): Alliance Foundation Trials Opens Its First Gynecological Cancer Study
(June): Sanofi Partnering with Leading Academic Cooperative Groups to Study Amcenestrant in the Adjuvant Setting for Patients with Estrogen Receptor-Positive Breast Cancer

2020
Fall Vol 10 No 2 (December)
- Message From the Group Chair - Monica M. Bertagnolli, MD
- Alliance Investigators Work to Bring Practice-Changing Treatment Through Registration Trials
  Alliance A011801 - HER2+ Breast Cancer
  Alliance A021502 - Colon Cancer
  Alliance A021602 - Neuroendocrine Tumors
  Alliance A041701 - Acute Myeloid Leukemia
- Alliance Announcements
  Alliance Appoints New Alliance Health Disparities Committee Chair - Lucile L. Adams-Campbell
  Alliance Imaging Committee Expands to Include New Subcommittee on Theranostics
  Recap: Alliance/AFT Abstracts at 2020 SABCS Meeting
  Recap: Alliance/AFT Abstracts at 2020 ASH Meeting
- New Trials Alert
  Alliance A191901 - Support for Patients with Breast Cancer
  Alliance A021804 - Advanced Neuroendocrine Cancer
  Alliance A031901 - Metastatic Urothelial Carcinoma
  Alliance A071702 - Somatically Hypermutated Recurrent Glioblastoma
- Closed to Accrual: Alliance A011502 (ABC Trial)
- Alliance in the News
  Precision Treatment Advances Improve Survival in Women with Aggressive HER2+ Breast Cancer
  Black Race an Independent Predicator of Poor Survival Among Young Adults with AML
  Ohio State Creates Clara D. Bloomfield Center for Leukemia Outcomes Research
  American Cancer Society Announces New Members and Officers of Board of Directors
- PDF Version
Fall Vol 10 No 1 (October)
- Alliance Activates New Trials, Enrolls Participants in Midst of COVID-19 Pandemic (snapshots)
  Alliance A171901 - Advanced non-small cell lung cancer
  Alliance A091902 - Angiosarcoma
  Alliance A021806 - Resectable pancreatic cancer
  Alliance A081801 - Non-small cell lung cancer
  Alliance A221805 - Peripheral neuropathy/colorectal cancer
  Alliance A151804 - National biorepository for immune-related adverse events
  Alliance A031803 - Invasive bladder cancer
- Alliance - COVID-19 Updates and Resources (Alliance members)
- Who We Are - Defining, Understanding All Four Distinct Alliance Entities
- 2020 Alliance Fall Virtual Group Meeting Convenes Nov 4-7
- Recent Alliance-related News & Publications
  Alliance Appoints Electra D. Paskett PhD Cancer Control Program Director, PI of Alliance NCORP Research Base
  ASCO Highlights Alliance Investigators
  Recap :: 2020 Alliance/ASCO Abstracts
  Alliance Researchers Identify Gene Variant Linked to Drug-Induced Hypertension from Bevacizumab
  What Happened to the US Cancer Cooperative Groups? A Status Update Ten Years After the Institute of Medicine Report
  The National Clinical Trials Network and the Cooperative Groups: The Road Not Taken
- PDF Version

2019
Winter Vol 9 No 4 (December)
- Building Community Trust to Grow Underrepresented Minority Clinical Trial Participation in Southeastern Wisconsin
  Alliance Principal Investigator Perspectives - Tina W. F. Yen, MD, MS, Froedtert and the Medical College of Wisconsin LAPS
- The Times They Are a-Changin'
  Alliance Transplant and Cell Based Therapies Committee - Miguel-Angel Perales, MD
- Lessons Learned: Research Implementation Strategies for Community Based Clinics Participating in Clinical Trials
  Alliance Health Disparities Committee - Courtney Chun, University of Hawaii Cancer Center
- 2019 Alliance/ASH Abstracts
- 2019 Alliance/SABCS Abstracts
- Spotlight on Alliance Trials Activated in 2019
- Alliance Foundation Special Project Allocation
- Recap: 2019 Alliance Fall Group Meeting | November 7-9
- Happy Holidays from Alliance
- PDF Version

Fall Vol 9 No 3 (November)
- Message From the Group Statistician - Sumithra J. Mandrekar, PhD
  Leveraging Statistical, Methodological Research to Advance Alliance Initiatives
- Optimizing Clinical Trials to Improve Anti-Cancer Immune Response
  Alliance Immuno-Oncology Committee - David Kozono, MD, PhD, Andrew B. Nixon, PhD, Elizabeth Mittendorf, MD, PhD
- 2019 Alliance Fall Group Meeting Convenes This Week - November 7-9
  Schedule, Agendas, E-Posters, Registration
- Spotlight on Alliance Trials
  Alliance A021703 - Metastatic colorectal cancer
  Alliance A071701 - Genetic testing in brain metastases
  Alliance A071801 - Metastatic brain cancer
  Alliance A221702 - Axillary reverse mapping
- PDF Version

Summer Vol 9 No 2 (July)
- Message From the Group Chair - Monica M. Bertagnolli, MD
- PI Perspective: Alliance Health Outcomes Committee
  Michelle Naughton, PhD and Amylou Dueck, PhD (Co-Chairs)
  Jackie Lafky, MS (Program Manager)
- Changing the Guard: Director and PI, Alliance Central Protocol Operations Program
  Gin F. Fleming, MD, FASCO and Olwen Hahn, MD
- Recent Alliance Protocol Activations
- Spotlight on Alliance Trials
  Alliance A091802 - Cutaneous squamous cell carcinoma
  Alliance A041701 - Chronic myeloid leukemia
  Alliance A031704 - Advanced renal cell cancer
  Alliance A031702 - Rare genitourinary tumors
- ICAREdata | Integrating Clinical Trials and Real World Endpoints
- Adding Value to the Alliance Clinical Trial Process
  Alliance Patient Advocate Committee
- Announcements
  -- Alliance Joins with ASCO, CancerLinQ and The MITRE Corporation to Publish Initial Set of Common Cancer Data Standards and Specifications Comprising mCODE (VIDEO))
  -- Recap: Alliance and Alliance Foundation Trials at 2019 ASCO
  -- Renewed NCI Investigational Agent Accountability Record Forms (DARFs)
  -- Call for Nominations + Applications: 2019/2020 Alliance Awards + Honors
  -- Alliance Appoints New Committee Chairs
- Alliance in the News
  -- GNS Healthcare Chosen to Present Discovery of New Clinical Predictors of Overall Survival in Metastatic Colorectal Cancer at ESMO 2019 in Collaboration with the Alliance for Clinical Trials in Oncology
  -- mCODE Improves EHR Data Standardization for Cancer Research
  -- First Patient Dosed in Phase III Study of E-Selectin Antagonist Uproleselan in AML (Alliance A041701)--ASCO 2019: CALGB 90601 (Alliance): Randomized, Double-blind, Placebo-controlled Phase III Trial Comparing Gemcitabine and Cisplatin with Bevacizumab or Placebo in Patients with Metastatic Urothelial Carcinoma
  --'Magic Mouthwash' Little Help for Radiation-Induced Mucositis (Alliance A221304)
  -- Magic mouthwash effective treatment for mouth sore pain caused by radiation therapy (Alliance A221304)
  -- Mouthwashes Show Promise in Reducing Chemo-Related Oral Mucositis Pain (Alliance A221304)
  -- Giving Drugs before Surgery Lowers the Risk of Prostate Cancer Returning (CALGB 90203)
  -- Study: Identifying colorectal cancer subtypes could improve treatment (CALGB/SWOG 80405)
  -- The Fight to Save the Bladder Turns to Genomics (Alliance A031701)
- PDF version
Winter Vol 9 No 1 (March)
- Registration Now Open - 2019 Alliance Spring Group Meeting
  New Contact for Group Meeting Logistics
- Professional Responsibility at the Forefront | Where Alliance Stands on Conflict of Interest
  James Bearden, MD and Jeffery Crawford, MD
  2019 Conflict of Interest (COI) Solicitation
- Message From the Group Statistician Sumithra J. Mandrekar, PhD
- Recent Alliance Protocol Activations
  Alliance A231602CD - Financial toxicity (blood cancers)
  Alliance A221701 - Oral stomatitis
  Alliance A041702 - Chronic lymphocytic leukemia
  Alliance A041703 - Acute lymphoblastic leukemia
- Guest Columnists
  Disparities Corner: Shoshana Rosenberg, ScD, MPH and Suzanne George, MD - Addressing Disparities in Care and Outcomes in Adolescent and Young Adult Cancer Patients
  Zoneddy Dayao, MD PI, University of New Mexico Comprehensive Cancer Center - Reality of Bringing Clinical Trials to the Medically Underserved
- Announcements
  Regulatory Column | NIH Single IRB (sIRB ) Implementation
  New Monthly IPEC Performance Updates for Data Submission Timeliness
  Call for Papers to Honor and Remember Dr. Arti Hurria
- Alliance in the News
  Treatment for Children with Leukemia Also Effective for Adolescents , Young Adults
  Exercise & Weight Loss to Prevent Breast Cancer Recurrence
  Celebrating NCORP Women in Science
  New Leukemia Drug is More Effective and Easier to Use
- PDF version

2018
Winter Vol 8 No 6 (December)
- Message From The Group Chair
  Happy Holidays!
- Guest Columnists
  Jeffrey A. Bogart, MD - Value of Local Therapy in an Era of Unprecedented Scientific Advancement
  Rena M. Conti, PhD and Gabriela Gracia, PhD - Treatment-Related Financial Difficulties: Patient and Practice Perspective
  Disparities Corner: Evan Kovac, MD, CM, FRCSC - Prostate Cancer Disparities in Minority Men, Challenges in Accruing to Clinical Trials
  Making Connections: Jennifer Dill, CCRP - Alliance Clinical Research Professionals At The Forefront
- Announcements
  Recently Activated Trials
  Call for Abstracts: Amerian College of Surgeons Quality and Safety Conference
- In Memoriam
  Arti Hurria, MD, FASCO - Leader in Geriatric Oncology
- PDF Version
Fall Vol 8 No 5 (October)
- Spotlight on Fall Group Meeting
  New Ideas, Promising Prospects Expected When Meeting Convenes November 1-3
  Helpful Tips for Navigating the Group Meeting
- Message From the Group Statistician
  Alliance Statistics and Data Center: On the Cutting Edge of Statistical, Methodological Research
- Guest Columnists
  Eva A. May, MBA - When Designing a Clinical Trial, Think Like a Marketing Manager
  Thomas C. Shea, MD - How We've Thrived in a "New" Marriage
- Announcements
  Recently Activated Trials
  Six Investigators Win Funding Awards from Cancer Control and Cancer Care Delivery Research Programs
- In Memoriam
  David Sugarbaker, MD - Renowned Thoracic Surgeon
- #Did You Know
  About Deadlines for Alliance Abstracts
  About Alliance Foundation Trials
- PDF Version
Summer Vol 8 No 4 (August)
- Spotlight on Trials
  Three New Alliance Protocol Activations
  Update - Two Trials Focus on Rare Population Subsets: Alliance A091302 and Alliance A091305
- Alliance in the News
  From Cattle Rancher to ASCO President: Monica Bertagnolli, MD, on her motivations and goals
  Geoffrey Uy, MD, to Lead Pivotal Phase III Trial for Patients with Acute Myeloid Leukemia (AML)
  Comparative Effectiveness of Decision Aids in Diverse Populations with Prostate Cancer (Alliance 191402CD)
  Associations of Artificially Sweetened Beverage Intake with Disease Recurrence and Mortality in Colon Cancer (CALGB 89803)
- Guest Columnists
  Richard M. Stone, MD - Intergroup Collaboration Emphasized in Era of Many New Drugs in Leukemia
  Alison Conlin, MD - Cancer Research in the Beautiful Pacific Northwest
  Disparities Corner | Haejin In, MD, MBA, MPH, FACS - Identifying Gastric Cancer Risk Through Cancer Disparities
- Announcements
  Call for Nominations: Charles G. Moertel Lecturer
  Call for Abstracts: CRPs and Oncology Nurses
  In Memoriam: Alliance Patient Advocates - Robert Harrison and Hank Porterfield
- Fall Group Meeting
  Schedule Now Available
  Registration Opens Late August
- #Did You Know
  About Meeting Materials from May 2018 (public site) or (member site)
  About Deadlines for Alliance Abstracts
  About Alliance Foundation Trials
- PDF Version
Summer Vol 8 No 3 (June)
- Spotlight on Trials
  Recent Alliance Protocol Activations
  Results from Alliance N1048 May Influence Future Treatment
  What's New in Alliance Cancer Care Delivery Research
  Sidedness as Key Indicator in Metastatic Colorectal Cancer (CALGB 80405)
  Alliance in the News
- Guest Columnist
  Ann L. Oberg, MD - SDC Update
- Announcements
  Hats Off! Giants in Cancer Care
  Operative Standards for Cancer Surgery
  NIH Public Access Policy Applies for Alliance Manuscripts
- Alliance at 2018 ASCO Recap
- Spring Group Meeting Recap
  Session Videos Now Available
  New Meeting App Stats
- #Did You Know
  About Alliance Roster Updates
  About Deadlines for Alliance Abstracts
  About Corrections in OPEN
  About Alliance Foundation Trials
- PDF Version
Spring Vol 8 No 2 (April)
- Spotlight on Trials
  Recent Alliance Protocol Activations
  Alliance Myeloma Committee
  New DCIS Special Study
  Work from Inaugural CCP Junior Faculty Award Recipients
- Alliance in the News
- Group Meeting Highlights
- Guest Columnists
  Eileen O'Reilly, MD and Jeffrey Meyerhardt, MD - Next Generation Approaches
- Announcements
- Steven Piantadosi, MD, PhD - New Associate Group Chair for Strategic Initiatives and Innovation
- Revisiting the Alliance Conflict of Interest Policy
- Will Conversion to CTCAE v5 Impact Alliance Trial?
- New Member Join Alliance Patient Advocate Committee
- RFP: Aflac Archie Bleyer Young Investigator Award
- In Memoriam: James F. Holland, MD and Karen Durham
- PDF Version
Winter Vol 8 No 1 (February)
- Spotlight on Trials:
  Recent Alliance Protocol Activations
  Alliance Experimental Therapeutics and Rare Tumor Committee
  Alliance Abstracts at Annual Meetings
- Alliance in the News
- Message From the Group Statistician
- Guest Columnists
  Ellis Levine, MD - The Good Fight
  John P. Leonard, MD - The Argument for Simplicity in Clinical Trials During an Era of Precision Medicine
  Patty Spears and Coleen Crespo, MIS - Advocating to Measure What Matters to Patients
- Alliance Spring Group Meeting Registration Now Open
  Investigators Panel - Clinical Trial Obstacles and Overcoming Them
- Announcements
  New Members Join Alliance Patient Advocate Committee
  Alliance/ACS CRP to Present Clinical Trials Training Course at SSO Annual Meeting
  Call for Abstracts: Alliance CRP/Oncology Nursing Committees
  RFP: Aflac Archie Bleyer Young Investigator Award
  Did You Know? Alliance Website Tips
- PDF Version
2017
Winter Vol 7 No 5 (December)
- Recap: Alliance Fall Group Meeting
  Message From the Group Chair and Group Statistician
- Spotlight on Trials:
  Results From Alliance Trial Lead to U.S. FDA Approval of Ex ten ded Indic ation (CABOSUN - Alliance A031203)
  Recent Alliance Protocol Activations
  Ongoing Trials - Alliance A011104 and Alliance A011106
- Alliance at ASH 2017
- Alliance at SABCS 2017
- Announcements: Awards + Honors
  Alliance Most Significant Manuscripts
  Alliance Scholar Award
- Announcements: General
  Service Recognition: Alliance Patient Advocate Committee Members
  In Memoriam:
  Jack Whelan
  Patrick Gavin, RPh
  Jimmie C. Holland, MD
- Alliance/ASCO Abstract Submission Deadline
- Featured Columns
  Meet the Alliance Executive Officers
  Alliance Disparities Committee Corner
  Did You Know? Alliance Website Tips
- Holiday Closures
- PDF Version
Fall Vol 7 No 4 (October)
- Alliance Fall Group Meeting Convenes
- Spotlight on Trials: Recent Alliance Protocol Activations
- Alliance in the News
- Announcements: Awards
  Daniel J. Sargent, PhD, Memorial Fellowship in Innovative Clinical Trial Design and Methods
  Alliance Cancer Care Delivery Research Committee Pilot Project Award
  Alliance Cancer Control Program Pilot Project Award and Junior Investigator Award
- Announcements: General
  New Alliance Investigator Course Successfully Introduced at Spring Meeting
  New Changes to CTMB Audit Guidelines
- Featured Columns
  Alliance Disparities Committee Corner
  Focus on: Alliance/American College of Surgeon Clinical Research Program (ACS CRP)
- Did You Know? Alliance Website Tips
- Thanksgiving Closure
- PDF Version
Summer Vol 7 No 3 (August)
- Spotlight on Alliance Trials
  CALGB (Alliance) 10603 | FDA Approves New Combination Treatment for AML
  Alliance 221208 | Managing Brain Radionecrosis (BeSt Trial)
  Alliance A091202 | Intervention for Myxoid Liposarcoma
  Alliance A091305 | Rare Tumor Subset for Advanced Anaplastic Thyroid Cancer
- In the News
- Protocols
  Recent Alliance Protocol Activations
- Alliance at ASCO 2017
- Staff & Members
  Meet New Alliance Board of Directors and Executive Committee
  Meet New Alliance Leadership
  Alliance Members on the Move
- Announcements
  What Alliance Members Need to Know About CTEP's New Registration and Credentialing Repository (RCR)
- Featured Columns
  Alliance Breast Committee Member Survey
  Alliance Disparities Committee Corner
- Did You Know? Alliance Website Tips
- Alliance Mission: By the Words
- PDF Version
Winter Vol 7 No 1 (February)
- Message From the Group Statistician
- New Co-Chairs to Lead Alliance Cancer in the Elderly Committee
- Alliance Leaders Assume New Posts
- Protocols
  Recent Alliance Protocol Activations
- Spotlight on Alliance Trials
  CALGB (Alliance) 100104 | Alliance Trial Results Lead to FDA Approval
  Alliance A021302 | Gastric Cancers
  Alliance A061402 | Solitary Plasmacytoma of the Bone
  Alliance A091302 | Hürtle Cell Thyroid Cancer
- CRP Perspective (new recurring column)
  "A Rose (or Roger) By Any Other Name"
- Staff & Members
  Meet New Alliance Leadership
  Alliance Members on the Move
  Call for Nominations: Alliance Respiratory Committee Co-Chair
- Member Services
  Undertanding Alliance Member Accrual Credits
  Understanding the Importance of CTEP-IAM Registration
- CTMB Update
- Did You Know? Alliance Website Tips
- Alliance Mission: By the Words
- PDF Version

2016
Winter Vol 6 No 5 (December)
- Message From the Group Chair
- Daniel J. Sargent Alliance Memorial Service Video
- Alliance Leaders Elected to ASCO Posts
- Recent Alliance Protocol Activations
- Meet New Alliance Leadership
- New Alliance Staff
- Alliance Names Most Notable, Original Manuscripts
- Annual Alliance Research Awards
- Recap: 2016 ASH Meeting
- Learm more about NCI-Sponsored Precision Medicine Trials
- New NCI Liaisons to Alliance Cancer Control Program
- Alliance Institutional Best Practices Blog (member site)
- Alliance Mission: By the Words
- PDF Version
Fall Vol 6 No 4 (October)
- Registration Now Open for Alliance Fall Group Meeting
- In Memoriam: Daniel J. Sargent, PhD
- Four Investigators Receive Funding Through Alliance Cancer Control Program
- Alliance Researcher Approved for $5.45M PCORI Funding Award
- NCI Selects Alliance Researcher to Co-Chair CCDR Coordinating Committee
- Results from NCCTG (Alliance) N107C Trial for Patients with Metastatic Brain Tumors
- New Alliance Committee Leadership
- Recent Alliance Protocol Activations
- Did You Know? Three Alliance Website Tips
- PDF Version
Summer Vol 6 No 3 (August)
- Two Leading Cancer Researchers to Co-Chair Alliance Breast Committee
- Meet New Alliance Leaders
- Greetings from Alliance Statistics and Data Center
- Spotlight on Patient Advocacy: Resolution
- What's New? Alliance Member Services Enhancement Task Force
- Spotlight on Alliance Trials:
  NCCTG (Alliance) N0574
  
  Alliance A031203
  In the News:
  
  Alliance A011401
  CALGB/SWOG/Alliance 80405
- Alliance On the Move:
  New Staff
  Members Making Strides
- Call for Nominations:
  Moertel Lecture
  Alliance Community Oncology Committee Co-Chair
  Alliance Prevention Committee Co-Chair
- Did You Know? Four Alliance Website Tips
- PDF Version
Spring Vol 6 No 2 (May)
- Alliance Convenes 2016 Spring Group Meeting May 12-14
- Thirteen Years of Service for Co-Chairs of the Alliance Breast Committee
- CALGB 10603 (RATIFY) Study Results in FDA Breakthrough Therapy Desgination
- Alliance Welcomes New Staff
- In Memoriam: Egbert C. Brown and Kathleen W. Rao, PhD, FACWG
- Funding Opportunities: CCP Pilot Project CCP Jr. Faculty Awards CCDR Pilot Project
- Alliance Foundation Award Opportunities: Richard L. Schilsky CALGB Achievement Award Alliance Scholar Award
- PDF Version
Spring Vol 6 No 1 (March)
- Alliance Researcher Approved for PCORI Award
- Chicago 'Top Doctors'
- Alliance CRP Committee Improves Training
- Alliance Study to Assess Post RT Treatment Options
- Reducing Cancer-related Fatigue Focus of Alliance Study
- Recap: 2015 ASH Meeting
- Did You Know? Searchable Alliance Pubs App
- Positions Available: Alliance Breast Committee, Alliance Oncology Nursing Committee and Alliance Pharmacy Committee
- Renewal of DARF + IR Forms
- PDF Version

2015
Winter Vol 5 No 6 (December)
- Message From the Group Chair
- First Targeted Therapy for Patients with High-Risk AML
- Alliance, GNS Launch Big Data Initiative to Transform Metastatic Colorectal Cancer
- Meet New Alliance Leadership
- New Leadership, Staff in Alliance Statistics Unit
- Alliance Data Management Unit Consolidation
- Alliance Receives 'The Charlie Award' from CEO Roundtable on Cancer
- Alliance Names Most Notable, Original Manuscripts
- Annual Alliance Research Awards
- Alliance Patient Advocate Committee Update
- Alliance Mission: By the Words
- PDF Version
Fall Vol 5 No 5 (November)
- Alliance Convenes 2015 Fall Group Meeting November 5-8
- Introducing Alliance Foundation Trials, LLC (AFT)
- Alliance Researchers Explore Use of Aspirin to Treat Breast Cancer
- Deadlines for Upcomnig Alliance Abstracts
- Four Investigators Receive Funding Awards from Alliance Cancer Control Program (updated)
- New Study Chair Appointments | Alliance A071101
- On the Move: Alliance Members + Welcome New Staff
- PDF Version
Fall Vol 5 No 4 (October)
- AFT Launches New PALLAS Trial
- Pivotal Alliance Thyroid Cancer Trials: A091302 and A091305
- Alliance Researchers Approved for PCORI Awards
- Meet the Alliance Member Services Enhancement Task Force
- Edith Perez Steps Down as Vice Chair
- CRP Resources Now Available
- New CRP Breakout Sessions for Alliance Fall Group Meeting
- Upcoming Pilot Project from the A-ONC Team
- A-OCN Seeks GU Liaison
- Alliance Hosts SOCRA Exam
- Upcoming Conferences
- PDF Version

In Memoriam: Daniel J. Sargent, PhD | Alliance Memorial Service Video (November 2016) | Celebration of Life Tribute Book (pdf)