Features Archives - Alliance for Clinical Trials in Oncology

Three-Week Radiation Course a Safe Option for Breast Cancer Patients Undergoing Reconstruction, Alliance Trial Shows

October 28, 2026

Published in Journal of Clinical Oncology, findings provide evidence that shortening radiation schedule does not sacrifice treatment success or impair reconstruction efforts Results of a national clinical trial led by the Alliance for Clinical Trials in Oncology in conjunction with NRG Oncology and the Canadian Cancer Trials Group show that a shorter, three-week radiation schedule…

Cancer Control

Features

Alliance Announces FDA Approval of Atezolizumab Based on Results from the Phase III ATOMIC Trial for Patients with Stage III dMMR Colon Cancer

October 9, 2026

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has approved the immunotherapy drug atezolizumab (Tecentriq®) in combination with fluoropyrimidine and oxaliplatin chemotherapy, for the adjuvant treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR). The approval is based on…

Gastrointestinal Cancer

Features

Alliance Foundation Trials and Natera Announce AFT-70 NAVIGATE

October 5, 2026

A Global, Randomized, Phase III Trial Evaluating Genentech’s Oral Selective Estrogen Receptor Degrader (SERD) with SignateraTM MRD-Guided CDK4/6 Inhibitor Therapy in ER-Positive/HER2-Negative Early-Stage Breast Cancer Trial will utilize Natera’s ultrasensitive MRD test, Signatera Genome with Phased and Structural Variants, paired with giredestrant monotherapy, Genentech’s oral SERD, with the objective to spare patients from unnecessary CDK4/6…

Breast Cancer

Features

Advancing Research in Resected Non-Small Cell Lung Cancer: An Update on ALCHEMIST Chemo-IO Trial/Alliance A081801

September 15, 2026

The ALCHEMIST Chemo-IO Trial (Alliance A081801) trial, led by Jacob Sands, MD, at Dana-Farber Cancer Institute, together with ALCHEMIST study chair David Kozono, MD, PhD, continues to advance research aimed at improving treatment for patients with resected non-small cell lung cancer (NSCLC). Alliance A081801, part of the ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and…

Respiratory Cancer

Features

Alliance Research at ASCO 2026

May 30, 2026

The Alliance for Clinical Trials in Oncology and Alliance Foundation Trials will present a diverse portfolio of research at the 2026 ASCO Annual Meeting, taking place May 29-June 2 in Chicago, Illinois, spanning breast, gastrointestinal, genitourinary, thoracic, neuro-oncology, health outcomes, and data science. Collectively, these studies reflect the continued leadership of the Alliance in practice-changing clinical trials, translational biomarker…

Breast Cancer Gastrointestinal Cancer Genitourinary Cancer Respiratory Cancer

Features

April is Head and Neck Cancer Awareness Month

April 20, 2026

Alliance clinical trials currently open to patients and survivors of these cancers Did you know that cancers in the head and neck area, including the mouth, throat, nasal cavity and voice box, account for about 4% of all new cancers diagnosed in U.S. each year? Major risk factors include smoking cigarettes as well as the…

Cancer Control Experimental Therapeutics

Features

Alliance Marks Adolescent and Young Adult Cancer Awareness Week

April 7, 2026

Connecting AYA patients and survivors to open clinical trials Each year, about 85,000 adolescents and young adults (AYA) between the ages of 15 and 39 are diagnosed with cancer in the United States. According to the National Cancer Institute, this represents about 4% of all new cancer diagnoses. Depending on age and specific diagnosis, many…

Cancer Control Experimental Therapeutics Leukemia Neuro-Oncology

Features

Alliance Spotlights New Advances and Active Clinical Trials During Multiple Myeloma Awareness Month

March 23, 2026

During Multiple Myeloma Awareness Month, the Alliance for Clinical Trials in Oncology and the Alliance Foundation Trials (AFT) are spotlighting several innovative research studies designed to improve treatment and long-term outcomes for people diagnosed with this rare blood cancer. Multiple myeloma is a blood cancer that forms in plasma cells, an important part of the…

Myeloma

Features

Alliance Highlights New and Open Colorectal Cancer Trials in March

March 15, 2026

This March, join the Alliance for Clinical Trials in Oncology (Alliance) and the Alliance Foundation Trials (AFT) in spotlighting colorectal cancer, the second leading cause of cancer-related death in the United States, behind only lung cancer, according to the National Cancer Institute. Last year, an estimated 155,000 Americans received a diagnosis of colon or rectal…

Cancer Control Gastrointestinal Cancer

Features

Upcoming Alliance Webinar Highlights Latest Cancer Treatment Advances

February 21, 2026

March 16 event features researchers, patient advocates highlighting key findings published recently View the YouTube recording of the March 16 webinar. The Alliance for Clinical Trials in Oncology will host a free, public webinar on Monday, March 16, 2026, from 1 pm to 2 pm CT showcasing key cancer research from Alliance investigators presented at…

Breast Cancer Leukemia Myeloma

Features

Categories

Alliance Committee

Browse by Year