At the Alliance for Clinical Trials in Oncology, we love sharing stories that show what’s happening in cancer research right now. Whether it’s a new clinical trial, a scientific breakthrough, or the work of one of our dedicated investigators, we want people to see the progress being made, and the real humans behind it. These…
Published results show adjuvant atezolizumab plus mFOLFOX6 significantly reduces recurrence risk and delivers the first proven immunotherapy benefit in early stage dMMR disease. A new study from researchers at the Alliance for Clinical Trials in Oncology (Alliance) shows that patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR) had significantly…
During Multiple Myeloma Awareness Month, the Alliance for Clinical Trials in Oncology and the Alliance Foundation Trials (AFT) are spotlighting several innovative research studies designed to improve treatment and long-term outcomes for people diagnosed with this rare blood cancer. Multiple myeloma is a blood cancer that forms in plasma cells, an important part of the…
Alliance researchers presented new research at the Society of Surgical Oncology (SSO) 2026 Annual Meeting, held March 5-7 in Phoenix. SSO brings together surgical oncologists, researchers and trainees from around the world to discuss the latest advances in cancer care. It mobilizes a broad community of surgeons who strive to enhance patient care across all…
A new clinical trial led by the Alliance for Clinical Trials in Oncology will investigate if a combination of drug therapies after radiation therapy improves outcomes for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma, a type of brain cancer. Supported in part by a grant from the National Cancer Institute, the study (Alliance A072301) will…
This March, join the Alliance for Clinical Trials in Oncology (Alliance) and the Alliance Foundation Trials (AFT) in spotlighting colorectal cancer, the second leading cause of cancer-related death in the United States, behind only lung cancer, according to the National Cancer Institute. Last year, an estimated 155,000 Americans received a diagnosis of colon or rectal…
Twice-daily radiation therapy associated with improved survival in limited-stage, small-cell lung cancer Immunotherapy given during and after chemoradiation did not improve survival for study participants with limited-stage, small-cell lung cancer (SCLC) according to the results of an international clinical trial, NRG-LU005, led by NRG Oncology in collaboration with the Alliance for Clinical Trials in Oncology. The…
Study will use two oral targeted cancer therapies for adults over 65 The Alliance for Clinical Trials in Oncology has launched a new clinical trial for adults who need first-line therapy for chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study (Alliance A042302) will explore whether combining two targeted medicines, zanubrutinib and sonrotoclax,…
At the Alliance for Clinical Trials in Oncology (Alliance), we share stories highlighting the progress and impact of cancer research. By shining a light on new clinical trials, scientific discoveries, and the achievements of our investigators, we showcase the progress being made against cancer and the people driving it forward. These stories raise awareness of…
In time for Colorectal Cancer Awareness Month in March, the Alliance for Clinical Trials in Oncology has launched a new clinical study aimed at helping improve how patients with colorectal cancer share information about the genetic risks to their family members. Supported by grants from the National Cancer Institute, the trial, “Family Communications After Genetic…