PRO-TECT trial shows remote symptom monitoring reduces health disparities and emergency visits while improving quality of life in underserved populations New results from an Alliance Foundation Trials (AFT) study reveal that a simple weekly electronic symptom check-in with care team, significantly improves the quality of life for individuals undergoing treatment for advanced cancer. The study…
Addition of Palbociclib to Standard Maintenance Therapy Demonstrates Significant Progression-Free Survival Benefit in HR+, HER2+ Advanced Breast Cancer Alliance Foundation Trials, LLC (AFT) today announced the publication of the pivotal phase III PATINA study (AFT-38) in the New England Journal of Medicine (NEJM), marking a major milestone for patients with hormone receptor–positive (HR+), human epidermal…
A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that abemaciclib, an oral cancer drug, may slow tumor growth in patients with aggressive meningiomas that have specific genetic mutations. This primary analysis of Alliance A071401 is published in Nature Medicine. Meningiomas, tumors that grow in the membranes that surround…
Data from a major U.S. clinical trial from the Alliance for Clinical Trials in Oncology has uncovered a genetic factor that may inform how to optimize the dosing of abiraterone, a widely used hormone treatment for advanced prostate cancer. Published in Clinical and Translational Science, this secondary analysis of Alliance A032201 could lead to more…
A blood test could help doctors decide which patients with colon cancer should receive anti-inflammatory medication along with chemotherapy after surgery, according to new study in JAMA Oncology. Based on data from an Alliance for Clinical Trials in Oncology study, this finding could lead to more personalized treatments and better outcomes for patients. Colon cancer…