NEWS

Clinical Trials Focus on Cancer Prevention

February 5, 2026

The Alliance for Clinical Trials in Oncology is committed not only to finding new and better ways to treat cancer but also to identifying ways to help prevent cancer from occurring in the first place.

According to the National Cancer Institute, cancer prevention is any action taken to lower the chance of developing cancer. In addition to the physical challenges and emotional distress caused by cancer, the high cost of car


Randomized Trial Finds Drug Therapy Reduces Hot Flashes During Prostate Cancer Treatment

February 2, 2026 - A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes compared to the placebo in men receiving hormone therapy for prostate cancer. This primary analysis of Alliance A222001 is published in the Journal of Clinical Oncology.

“Oxybutynin demonst


Alliance Foundation Trials Phase III PATINA Study Results Published in the New England Journal of Medicine

January 28, 2026

Addition of Palbociclib to Standard Maintenance Therapy Demonstrates Significant Progression-Free Survival Benefit in HR+, HER2+ Advanced Breast Cancer

Alliance Foundation Trials, LLC (AFT) today announced the publication of the pivotal phase III PATINA study (AFT-38) in the New England Journal of Medicine (NEJM), marking a major milestone for patients with


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